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SCN2B

Official Full Name

sodium channel, voltage-gated, type II, beta
Overview

forms a voltage gated sodium channel with alpha subunit; may modulate sodium channel expression in neurons
Synonyms

SCN2B; sodium channel, voltage-gated, type II, beta; sodium channel subunit beta-2; Neuronal voltage gated sodium channel beta 2 subunit; Scn 2b; SCN2B_HUMAN; Sodium channel beta 2 subunit; Sodium channel subunit beta 2; Sodium channel voltage gated type II beta; Sodium channel voltage gated type II beta polypeptide; Sodium channel beta 2; sodium channel, voltage-gated, type II, beta polypeptide; SCNB2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Homo sapiens (Human)
Human
Rat
Rattus norvegicus (Rat)
Rhesus Macaque
Zebrafish

Source

E.coli
E.coli expression system
HEK293
Human Cell
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
hFc
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SCN2B-697H	Recombinant Human SCN2B Protein, His-tagged	E.coli	His		Inquiry
Human	SCN2B-8616H	Recombinant Human SCN2B protein, hFc-tagged	HEK293	hFc	Met1-Ala159	Inquiry
Human	SCN2B-31351TH	Recombinant Human SCN2B	Wheat Germ	N/A	215 amino acids	Inquiry
Human	SCN2B-2536H	Recombinant Human SCN2B, GST-tagged	E.coli	GST	28-160aa	$319 / 25ug
Human	SCN2B-310H	Recombinant Human SCN2B, His tagged	Human Cell	His		Inquiry
Human	SCN2B-975HCL	Recombinant Human SCN2B cell lysate	Human Cell	N/A		Inquiry
Human	SCN2B-1280HCL	Recombinant Human SCN2B cell lysate	Human Cell	N/A		Inquiry
Human	SCN2B-457HF	Recombinant Full Length Human SCN2B Protein	In Vitro Cell Free System		215 amino acids	Inquiry
Rat	SCN2B-5263R	Recombinant Rat SCN2B Protein	Mammalian Cell	His		Inquiry
Rat	SCN2B-4922R	Recombinant Rat SCN2B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SCN2B-4922R-B	Recombinant Rat SCN2B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Homo sapiens (Human)	RFL18899HF	Recombinant Full Length Human Sodium Channel Subunit Beta-2(Scn2B) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (30-215)	Inquiry
Rattus norvegicus (Rat)	RFL32011RF	Recombinant Full Length Rat Sodium Channel Subunit Beta-2(Scn2B) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (30-215)	Inquiry
Rhesus Macaque	SCN2B-4100R	Recombinant Rhesus monkey SCN2B Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SCN2B-3917R	Recombinant Rhesus Macaque SCN2B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	SCN2B-3917R-B	Recombinant Rhesus Macaque SCN2B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	SCN2B-4815Z	Recombinant Zebrafish SCN2B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SCN2B Related Articles

SCN2B involved in several pathways and played different roles in them. We selected most pathways SCN2B participated on our site, such as Axon guidance, Developmental Biology, Interaction between L1 and Ankyrins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Axon guidance	PPP3R2;PITPNA;SEMA5A;EVL;RASGEF1A;CFL1;KRAS;COL4A3;RHOGA
Developmental Biology	EFNA4;PAQR3A;DUSP10;ITGB1B.1;TRPC5;RASGEF1A;RHOC;KALRN;EFNB2
Interaction between L1 and Ankyrins	ANK2B;SCN2A;KCNQ3;NADL1.1;SCN3A;SCN8A;SCN4A;SCN2B;KCNQ2
L1CAM interactions	SCN9A;RANBP9;CNTN1;DCX;NADL1.1;SCN3A;SCN8A;KCNQ2;EZRA

SCN2B has several biochemical functions, for example, sodium channel regulator activity, voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Some of the functions are cooperated with other proteins, some of the functions could acted by SCN2B itself. We selected most functions SCN2B had, and list some proteins which have the same functions with SCN2B. You can find most of the proteins on our site.

Function	Related Protein
sodium channel regulator activity	SGK2;FGF13;SCN1BB;SCN2B;FXYD3;SCN1BA;FXYD2;CAV3;SGK2A
voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN2B;SCN5A;SCN1B;SCN3B

SCN2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCN2B here. Most of them are supplied by our site. Hope this information will be useful for your research of SCN2B.

Szpyt, J; Lorenzon, N; et al. Three-Dimensional Localization of the alpha and beta Subunits and of the II-III Loop in the Skeletal Muscle L-type Ca2+ Channel. JOURNAL OF BIOLOGICAL CHEMISTRY 287:43853-43861(2012).

Whitaker, WRJ; Faull, RLM; et al. Comparative distribution of voltage-gated sodium channel proteins in human brain. MOLECULAR BRAIN RESEARCH 88:37-53(2001).