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SCO1

Official Full Name

SCO cytochrome oxidase deficient homolog 1
Overview

Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.
Synonyms

SCO1; SCO cytochrome oxidase deficient homolog 1 (yeast); SCO (cytochrome oxidase deficient, yeast) homolog 1 , SCOD1; protein SCO1 homolog, mitochondrial; SCOD1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SCO1-167H	Recombinant Human SCO1 protein, His-tagged	E.coli	His		Inquiry
Human	SCO1-2540H	Recombinant Human SCO1, GST-tagged	E.coli	GST	1-301aa	$319 / 25ug
Human	SCO1-168H	Recombinant Human SCO1	E.coli	N/A		Inquiry
Human	SCO1-2026HCL	Recombinant Human SCO1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SCO1-763H	Recombinant Human SCO1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	SCO1-6243H	Recombinant Human SCO1 Protein (Gly132-Ser301), N-GST tagged	E.coli	N-GST	Gly132-Ser301	Inquiry
Mouse	SCO1-14769M	Recombinant Mouse SCO1 Protein	Mammalian Cell	His		Inquiry
Mouse	SCO1-7941M-B	Recombinant Mouse SCO1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SCO1-7941M	Recombinant Mouse SCO1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Sco1-5718M	Recombinant Mouse Sco1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SCO1 Related Articles

SCO1 involved in several pathways and played different roles in them. We selected most pathways SCO1 participated on our site, such as Electron Transport Chain, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Electron Transport Chain	ATP5S;COX6C;COX6A2;NDUFC2-KCTD14;UCP3;COX8A;SCO1;COX4I1;COX11
Gene Expression	TYW5;EEF2;ZNF167;ZNF713;HNRNPL2;SEC61B;ESRRG;ZNF556;ESR2B
Generic Transcription Pathway	ZNF786;CDK9;SCO1;MED10;ZNF556;ZNF614;ZNF670;ZNF350;ZNF311
Metabolism	CYP51A1;DDAH2;CHST9;SLC25A10;CERS3B;AQP1A.1;UROC1;CYP2F1;UGT1B4
Respiratory electron transport	C2orf56;NDUFAF4;LRPPRC;ETFB;COX14;SURF1;NDUFAF7;NDUFAF5;SCO1
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	NDUFAF7;ETFB;COX11;C20orf7;COX16;COX14;SLC25A14;TACO1;FAM36A
TP53 Regulates Metabolic Genes	COX16;COX18;PRDX2;SCO1;FAM36A;LRPPRC;SURF1;SESN3;COX14
The citric acid (TCA) cycle and respiratory electron transport	NDUFAF5;UCP2;PDK3;SCO1;ETFB;ETFA;COX14;NDUFAF4;PDP2

SCO1 has several biochemical functions, for example, copper ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SCO1 itself. We selected most functions SCO1 had, and list some proteins which have the same functions with SCO1. You can find most of the proteins on our site.

Function	Related Protein
copper ion binding	LOXL2B;SCO2;LOXL5A;P2RX2;SOD1;P2RX4;ABHD1;TYRP1;MOXD2
protein binding	PPP1R9B;IFT43;AMELX;GTPBP10;TFRC;CHIC2;TAP1;SYT2;TPPP

SCO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCO1.

NDUFS7; SLC25A13

Knowles, TT; Alleman, AR; et al. Characterization of the major antigenic protein 2 of Ehrlichia canis and Ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis. CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY 10:520-524(2003).

Galvez, F; Reid, SD; et al. Isolation and characterization of mitochondria-rich cell types from the gill of freshwater rainbow trout. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 282:R658-R668(2002).