Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SCRIB

  • Official Full Name

    scribbled homolog (Drosophila)

  • Overview

    This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
  • Synonyms

    SCRIB; scribbled homolog (Drosophila); protein scribble homolog; KIAA0147; SCRB1; Vartul; CRIB1; SCRIB1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SCRIB-01HL Recombinant Human SCRIB Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SCRIB-14775M Recombinant Mouse SCRIB Protein Mammalian Cell His
Mouse SCRIB-7947M Recombinant Mouse SCRIB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SCRIB-7947M-B Recombinant Mouse SCRIB Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SCRIB-1657Z Recombinant Zebrafish SCRIB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SCRIB Related Articles

SCRIB involved in several pathways and played different roles in them. We selected most pathways SCRIB participated on our site, such as Hippo signaling pathway, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCRIB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hippo signaling pathwayJUB;LATS2;ITGB2;AREG;WNT10B;WNT16;WNT9B;CTNNA2;YWHAZ
Viral carcinogenesisUBE3A;CCND1;HDAC7A;PKM;SP100;STAT5B;HDAC2;HLA-F;ATP6V0D2

SCRIB has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SCRIB itself. We selected most functions SCRIB had, and list some proteins which have the same functions with SCRIB. You can find most of the proteins on our site.

Function Related Protein
protein bindingDES;SNX27;ID2;MYO7A;KLHDC3;CDK20;STX11;SFRP5;CNPY2

SCRIB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCRIB here. Most of them are supplied by our site. Hope this information will be useful for your research of SCRIB.

Crtam; PHLPP1; PHLPP2; Ywhae; Tmem173; Prkcd; Cdc42

Nguyen, MM; Rivera, C; et al. Localization of PDZ domain containing proteins discs large-1 and scribble in the mouse eye. MOLECULAR VISION 11:1183-1199(2005).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SCRIB Products

Required fields are marked with *

My Review for All SCRIB Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends