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SDCBP2

Official Full Name

syndecan binding protein (syntenin) 2
Overview

The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031.
Synonyms

SDCBP2; syndecan binding protein (syntenin) 2; syntenin-2; SITAC18; ST 2; MDA9; Melanoma differentiation associated gene 9; Pro TGF alpha cytoplasmic domain interacting protein 18; Syndecan binding protein 2; OTTHUMP00000029961; OTTHUMP00000029962; OTTHUMP00000029963; OTTHUMP00000029964; ST-2; SITAC;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SDCBP2-1360H	Recombinant Human SDCBP2	Mammalian Cell	His		Inquiry
Human	SDCBP2-2549H	Recombinant Human SDCBP2, His-tagged	E.coli	His	1-292aa	$319 / 25ug
Human	SDCBP2-385H	Recombinant Human syndecan binding protein (syntenin) 2, His-tagged	E.coli	His		Inquiry
Human	SDCBP2-2014HCL	Recombinant Human SDCBP2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SDCBP2-4038H	Recombinant Human SDCBP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	SDCBP2-1081H	Recombinant Human SDCBP2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	SDCBP2-4038H-B	Recombinant Human SDCBP2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Sdcbp2-5729M	Recombinant Mouse Sdcbp2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SDCBP2 involved in several pathways and played different roles in them. We selected most pathways SDCBP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SDCBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SDCBP2 has several biochemical functions, for example, protein C-terminus binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SDCBP2 itself. We selected most functions SDCBP2 had, and list some proteins which have the same functions with SDCBP2. You can find most of the proteins on our site.

Function	Related Protein
protein C-terminus binding	PDZD3;PEX5;ERCC2;BLOC1S2A;DST;PCGF1;CDK7;CLIC6;BAIAP2
protein binding	PRMT2;CENPK;FBXO3;CDC45;B2M;OPRD1;SRSF7;PPP1CC;CHERP
protein heterodimerization activity	NR2C2;CLNS1A;ENO2;Itgam&Itgb2;ABCG1;HIST1H4L;ADRB1;IRAK1;GABPA
protein homodimerization activity	CAMK2B;TREX2;ADIPOQ;LRRK2;SNF8;UGT1A6A;P2RX4;APOE;PRMT8

SDCBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDCBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDCBP2.

ZCCHC17; CT45A5; EIF1AD; CT45A3; TIFA