Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SEC63

  • Official Full Name

    SEC63 homolog (S. cerevisiae)

  • Overview

    The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
  • Synonyms

    SEC63; SEC63 homolog (S. cerevisiae); SEC63 like (S. cerevisiae); translocation protein SEC63 homolog; DNAJC23; ERdj2; PRO2507; SEC63L; SEC 63;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rhesus Macaque
  • Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SEC63-2569H Recombinant Human SEC63, His-tagged E.coli His 409-760aa
Human SEC63-1988HCL Recombinant Human SEC63 293 Cell Lysate HEK293 N/A
Human SEC63-3941H Recombinant Human SEC63 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse SEC63-14843M Recombinant Mouse SEC63 Protein Mammalian Cell His
Mouse Sec63-1003M Recombinant Mouse Sec63 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse SEC63-7994M-B Recombinant Mouse SEC63 Protein Pre-coupled Magnetic Beads HEK293
Mouse SEC63-7994M Recombinant Mouse SEC63 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL7566HF Recombinant Full Length Human Translocation Protein Sec63 Homolog(Sec63) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-760)
Mus musculus (Mouse) RFL2678MF Recombinant Full Length Mouse Translocation Protein Sec63 Homolog(Sec63) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-760)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL10111PF Recombinant Full Length Pongo Abelii Translocation Protein Sec63 Homolog(Sec63) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-761)
Rhesus Macaque SEC63-4130R Recombinant Rhesus monkey SEC63 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SEC63-3947R-B Recombinant Rhesus Macaque SEC63 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SEC63-3947R Recombinant Rhesus Macaque SEC63 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RFL32056SF Recombinant Full Length Saccharomyces Cerevisiae Protein Translocation Protein Sec63(Sec63) Protein, His-Tagged E.coli expression system His Full Length (1-663)
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) RFL18587SF Recombinant Full Length Schizosaccharomyces Pombe Translocation Protein Sec63(Sec63) Protein, His-Tagged E.coli expression system His Full Length (1-611)
Zebrafish SEC63-706Z Recombinant Zebrafish SEC63 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SEC63 involved in several pathways and played different roles in them. We selected most pathways SEC63 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
IRE1alpha activates chaperonesTPP1;SEC63;CTDSP2;HYOU1;SERP1;HDGF;FKBP14;SEC61B;YIF1A
Metabolism of proteinsTOMM6;C19orf10;THSD1;CCT7;BCS1L;TRAPPC3;ST8SIA3;TOMM40;IGFBP2A
Protein exportARXES1;SRPRB;SRP14;SLC38A8;IMMP1L;SPCS3;SRPR;SEC11C;SPCS1
Protein processing in endoplasmic reticulumUBE2D4;TRAF2;TUSC3;HYOU1;YOD1;HSPA5;MBTPS2;DNAJB11;SELS
Unfolded Protein Response (UPR)YIF1A;CXXC1;C19orf10;FKBP14;SEC63;DDX11;KLHDC3;SERP1;WIPI1
XBP1(S) activates chaperone genesSERP1;SEC63;WIPI1;CTDSP2;ASNA1;DNAJB9;C19orf10;DDX11;FKBP14

SEC63 has several biochemical functions, for example, poly(A) RNA binding, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC63 itself. We selected most functions SEC63 had, and list some proteins which have the same functions with SEC63. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingZNF638;EIF2S1B;CCDC55;RPP25;CSDA;GLRX3;RBM14;SECISBP2;ADARB1
protein bindingALCAM;RCN3;CCDC137;CD48;LGR4;UBA1;RABGGTB;FAM113A;RFESD
receptor activitySiglece;LRRN2;CUL5;Tnfrsf22;AGER;Pla2r1;VMN1R44;ERBB3B;MCC

SEC63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC63 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC63.

Nxn; PTP4A3; MCC; HLA-B; MAGEA6; MDM2; GSTK1; PHLDA3; NXN; cutF; 15-deoxy-delta(12,14; Irf1; Bub1b

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SEC63 Products

Required fields are marked with *

My Review for All SEC63 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends