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SELS

  • Official Full Name

    selenoprotein S

  • Overview

    This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    SELS; selenoprotein S; VCP-interacting membrane protein; VIMP; ADO15; SBBI8; SEPS1; AD-015;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SELS-2573H Recombinant Human SELS, GST-tagged E.coli GST 1-189aa
Human SELS-1983HCL Recombinant Human SELS 293 Cell Lysate HEK293 N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SELS involved in several pathways and played different roles in them. We selected most pathways SELS participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with SELS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein processing in endoplasmic reticulumCAPN1B;UBQLN4;NGLY1;HSPA8;UBE4B;ATF4B1;SEL1L;MAN1A;CUL1A

SELS has several biochemical functions, for example, ATPase binding, antioxidant activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SELS itself. We selected most functions SELS had, and list some proteins which have the same functions with SELS. You can find most of the proteins on our site.

Function Related Protein
ATPase bindingATP6V0A1;ATP6V1G3;FBL;PKD2;SDF2L1;TOR1AIP2;ATPIF1;LCK;ABCA1
antioxidant activityTRP53INP1;FABP1;PRDX6;S100A9;KDM3B;CAT;PRDX5;UBIAD1;APOM
enzyme bindingACAT1;SNRPD3;PUS7;CDC20;VAPB;NOXO1;UBE4B;NOTCH1;PIAS3
protein bindingZBTB22;MXD1;RIOK3;RIPPLY1;RAI2;KLHL41;MT1A;GPANK1;KNG1
receptor activityMED24;TLR6;SLC1A5;ITGB4;APLNR;V1RA8;UBXN6;NEO1;NPR2
ubiquitin-specific protease bindingDERL1;AMFR;VPS24;SART3;PARK2;RAD23A;CHMP3;PARK7;VCP

SELS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SELS here. Most of them are supplied by our site. Hope this information will be useful for your research of SELS.

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