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SEMA3E

  • Official Full Name

    sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

  • Overview

    Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    SEMA3E; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; SEMAH; semaphorin-3E; coll 5; KIAA0331; M sema H; M SemaK; coll-5; M-SEMAH; M-SemaK;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SEMA3E-932H Active Recombinant Human SEMA3E Protein, His-tagged Mammalian cells His Thr25-Ser775
Human SEMA3E-2574H Recombinant Human SEMA3E, His-tagged E.coli His C-211aa
Human SEMA3E-4042H Recombinant Human SEMA3E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SEMA3E-1908H Recombinant Human SEMA3E protein, His & T7-tagged E.coli His/T7 Arg32~Phe516 (Accession # O15041)
Human SEMA3E-4042H-B Recombinant Human SEMA3E Protein Pre-coupled Magnetic Beads HEK293
Human SEMA3E-6715H Recombinant Human SEMA3E Protein (Arg32-Phe516), N-His tagged E.coli N-His Arg32-Phe516
Mouse SEMA3E-14863M Recombinant Mouse SEMA3E Protein Mammalian Cell His
Mouse SEMA3E-8004M Recombinant Mouse SEMA3E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SEMA3E-8004M-B Recombinant Mouse SEMA3E Protein Pre-coupled Magnetic Beads HEK293
Mouse Sema3e-1909M Recombinant Mouse Sema3e protein, His-tagged E.coli His Ala581~Thr669 (Accession # P70275)
Zebrafish SEMA3E-4135Z Recombinant Zebrafish SEMA3E Mammalian Cell His
Chicken SEMA3E-5815C Recombinant Chicken SEMA3E Mammalian Cell His
Chicken SEMA3E-1907C Recombinant Chicken SEMA3E protein, His-tagged E.coli His Leu651~Asp740 (Accession # O42237)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SEMA3E Related Research Area

SEMA3E involved in several pathways and played different roles in them. We selected most pathways SEMA3E participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA3E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceRASGRP1;EPHA6;NRTN;Plxna2;ARPC4;RASGRP4;PAQR3A;NRG2A;ITGB1

SEMA3E has several biochemical functions, for example, chemorepellent activity, neuropilin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA3E itself. We selected most functions SEMA3E had, and list some proteins which have the same functions with SEMA3E. You can find most of the proteins on our site.

Function Related Protein
chemorepellent activitySEMA6D;SEMA3A;SEMA6DL;SEMA4A;SEMA4B;SEMA3BL;SEMA6E;SEMA3GA;UBE4A
neuropilin bindingVEGFA;SEMA3H;SEMA3A;SEMA3D;SEMA3B;Sema3f;SEMA3E;SEMA3GA;SEMA4E
protein bindingCIB2;NDE1;ZCCHC10;TP63;ITGB3B;AGTRAP;THRAP3;SETDB2;NR4A3
semaphorin receptor bindingSEMA3H;SEMA3D;SEMA3AB;SEMA3GA;SEMA5B;SEMA6C;SEMA3C;SEMA4BA;SEMA4B

SEMA3E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA3E here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA3E.

PLXND1

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