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SEMA7A
Official Full Name
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Background
The protein encoded by this gene binds to cell surfaces through a glycosylphosphatidylinositol (GPI) linkage. The;encoded glycoprotein is found on activated lymphocytes and erythrocytes. This protein may be involved in;immunomodulatory and neuronal processes. Defects in this gene can result in loss of bone mineral density (BMD). Three;transcript variants encoding different isoforms have been found for this gene.
Synonyms
JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1