sept2
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  • Official Full Name
  • septin 2
  • Background
  • SEPT2 belongs to an evolutionarily conserved family of genes that encode a P loop-based GTP-binding domain flanked by a polybasic domain and (usually) a coiled-coil region, and assemble into homo- and hetero-oligomers and filaments with key roles in cell division cytoskeletal dynamics and secretion. The SEPT2 gene codes for a protein with 361 amino acids and a molecular weight of 41.5 kDa.
  • Synonyms
  • SEPT2; septin 2; DIFF6, NEDD5,neural precursor cell expressed, developmentally down regulated 5; septin-2; hNedd5; KIAA0158; Pnutl3; DIFF6; hNEDD5; KIAA0158; Neural precursor cell expressed developmentally down regulated protein 5; Pnutl3; Protein NEDD5; SEPT2; NEDD-5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed developmentally down-regulated protein 5; DIFF6; NEDD5
Cat.#:SEPT2-762HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SEPT2 Protein, MYC/DDK-tagged
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Cat.#:SEPT2-2806HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Septin 2, His-tagged
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Cat.#:SEPT2-31399THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SEPT2, HIS-tagged
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Cat.#:SEPT2-31400THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SEPT2, HIS-tagged
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Cat.#:SEPT2-14892MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SEPT2 Protein
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Cat.#:SEPT2-5325RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SEPT2 Protein
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Cat.#:SEPT2-8473ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SEPT2
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Cat.#:SEPT2-1963HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SEPT2 293 Cell Lysate
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Involved Pathway

SEPT2 involved in several pathways and played different roles in them. We selected most pathways SEPT2 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPT2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Bacterial invasion of epithelial cells
PIK3CB; GAB1; ARPC5; MET; WAS; WASL; ARPC1A; SEPT3; RHOG; CBLC

Protein Function

SEPT2 has several biochemical functions, for example, GTP binding, enzyme regulator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPT2 itself. We selected most functions SEPT2 had, and list some proteins which have the same functions with SEPT2. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein GTPBP10; TUBA1A; RAB9A; RAB3C; GSPT2; ADSSL; RHOC; RAB11AL; GIMAP3; DNM1L
Function enzyme regulator activity
Related Protein SEPT2; GCLM; MTMR9; PPP1R7; APOC3; DPM2; RAB3GAP2; EIF2B1; BRCC3; PSMD1
Function protein binding
Related Protein CERS2; C10orf46; PAX3; DNAJA1; CCND3; ZCCHC7; TBC1D22B; KIAA1737; RGS3; KLRB1F
Function protein complex scaffold
Related Protein KLHL17; MAGI1B; AKAP1; WWC3; SMARCD1; CAV3; GNB2L1; SLC9A3R1; CAV1; ISCU

Interacting Protein

SEPT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPT2.
SEPT6; SEPT5; PLEKHF2; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; 2500771