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SERPINA5

  • Official Full Name

    serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

  • Overview

    The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012]
  • Synonyms

    SERPINA5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; PCI; PAI3; PAI-3; PCI-B; PROCI; PLANH3; plasma serine protease inhibitor; protein C inhibitor; plasminogen activator inhibitor-3; acrosomal serine protease inhibitor; plasminogen activator inhibitor III; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SERPINA5-486H Recombinant Human SERPINA5, His-tagged E.coli His
Human SERPINA5-855H Recombinant Human SERPINA5, His tagged Human Cell His
Human SERPINA5-1940HCL Recombinant Human SERPINA5 293 Cell Lysate HEK293 N/A
Human SERPINA5-5892H Recombinant Human SERPINA5 Protein (Ser43-Pro406), N-His tagged E.coli N-His Ser43-Pro406
Human SERPINA5-5890H Recombinant Human SERPINA5 Protein (His20-Pro406), C-His tagged Mammalian cells C-His His20-Pro406
Mouse SERPINA5-14926M Recombinant Mouse SERPINA5 Protein Mammalian Cell His
Mouse SERPINA5-8047M Recombinant Mouse SERPINA5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SERPINA5-8047M-B Recombinant Mouse SERPINA5 Protein Pre-coupled Magnetic Beads HEK293
Mouse SERPINA5-2816M Recombinant Mouse SERPINA5 Protein (25-405 aa), His-tagged Insect Cell His 25-405 aa
Rhesus Macaque SERPINA5-4148R Recombinant Rhesus monkey SERPINA5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SERPINA5-3965R Recombinant Rhesus Macaque SERPINA5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SERPINA5-3965R-B Recombinant Rhesus Macaque SERPINA5 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SERPINA5 involved in several pathways and played different roles in them. We selected most pathways SERPINA5 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesMBL2;F10;Serpina1c;FGA;SERPINA1A;CR1L;C7;SERPINE1;F13B

SERPINA5 has several biochemical functions, for example, acrosin binding, glycosaminoglycan binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINA5 itself. We selected most functions SERPINA5 had, and list some proteins which have the same functions with SERPINA5. You can find most of the proteins on our site.

Function Related Protein
acrosin bindingZP3;ZP2;SERPINA5
glycosaminoglycan bindingSPOCK3;TGFBR3;VIT;SPOCK2;SERPINA5;NDNF;CCDC80;TGFBR2;EGFLAM
heparin bindingCTGFB;NRP1A;ABP1;SERPINC1;ADAMTS8;RSPO4;MDK;VEGFA;KAL1
phosphatidylcholine bindingRASGRP1;APOA1A;VPS24;PCTP;RPE65;APOA4A;NF1;ESYT2;APOA4B.2
protease bindingPOLG;C10orf2;SERPINA1D;KIT;NFRKB;F3;CCBE1;TP53;A2M
protein bindingIL-8;PBX2;RNF182;PGM1;HMGB4;HSPA4L;NUSAP1;BAD;HIPK1
retinoic acid bindingCRABP1;UGT1A1;NR2F2;SERPINA5;CRABP1A;RARA;UGT1A3;PTGDSB;CRABP2
serine-type endopeptidase inhibitor activitySERPINA1;SPINT2;EPPIN;APPA;SERPINB10;SPINK4;WFDC6B;SERPINH1A;SERPINB13

SERPINA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINA5.

CBL; HRSP12; EP300; EPS8; COPS6; sbcD; PIAS4; RCHY1

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