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SESN2

Official Full Name

sestrin 2
Overview

This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
Synonyms

SESN2; sestrin 2; sestrin-2; DKFZp761M0212; HI95; SES2; SEST2; hypoxia induced gene 95; DKFZp761M02121;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Mammalian cells

Tag

Flag
GST
His
His (Fc)
Avi
His|T7
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SESN2-2605H	Recombinant Human SESN2, GST-tagged	E.coli	GST	1-117aa	$319 / 25ug
Human	SESN2-2606H	Recombinant Human SESN2, GST-tagged	E.coli	GST	C-term-350aa	$319 / 25ug
Human	SESN2-1930HCL	Recombinant Human SESN2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SESN2-1984H	Recombinant Human SESN2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	SESN2-6245H	Recombinant Human SESN2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	SESN2-1984H-B	Recombinant Human SESN2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	SESN2-1376HFL	Recombinant Full Length Human SESN2 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Mouse	Sesn2-8101M	Recombinant Mouse Sesn2 protein, His & T7-tagged	E.coli	His/T7	Ser41~Thr480 (Accession # P58043)	Inquiry
Mouse	Sesn2-5795M	Recombinant Mouse Sesn2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rhesus Macaque	SESN2-4160R	Recombinant Rhesus monkey SESN2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SESN2-3977R-B	Recombinant Rhesus Macaque SESN2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	SESN2-3977R	Recombinant Rhesus Macaque SESN2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	SESN2-4932Z	Recombinant Zebrafish SESN2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SESN2 Related Articles

SESN2 involved in several pathways and played different roles in them. We selected most pathways SESN2 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SESN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
p signaling pathway	COP1;CCND2A;CCNG2;CCNE2;GADD45BA;ZMAT3;STEAP3;SFN;TSC2

SESN2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SESN2 itself. We selected most functions SESN2 had, and list some proteins which have the same functions with SESN2. You can find most of the proteins on our site.

Function	Related Protein
protein binding	NUP98;USP10;LMLN;CCNB1IP1;RERG;RPP25L;SPEF2;ADIPOQ;ATP5B

SESN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SESN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SESN2.

SQSTM1; Ulk1; Sqstm1; MDM2; ATG13; ULK1; RB1CC1

Brazina, J; Svadlenka, J; et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. CELL CYCLE 14:375-387(2015).

Yang, JH; Kim, KM; et al. Role of sestrin2 in the regulation of proinflammatory signaling in macrophages. FREE RADICAL BIOLOGY AND MEDICINE 78:156-167(2015).