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SETD3

  • Official Full Name

    SET domain containing 3

  • Synonyms

    SETD3; SET domain containing 3; C14orf154, chromosome 14 open reading frame 154; histone-lysine N-methyltransferase setd3; FLJ23027; SET domain-containing protein 3; C14orf154; MGC87236; DKFZp761E1415;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SETD3-30077TH Recombinant Human SETD3, His-tagged E.coli His
Human SETD3-1927HCL Recombinant Human SETD3 293 Cell Lysate HEK293 N/A
Human SETD3-1985H Recombinant Human SETD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SETD3-048H Recombinant Human SETD3 Protein, His-tagged E. coli His 2-594
Human SETD3-01H Recombinant Human SETD3 Protein, His-tagged E.coli His 2-594
Human SETD3-1985H-B Recombinant Human SETD3 Protein Pre-coupled Magnetic Beads HEK293
Human SETD3-2943H Recombinant Human SETD3 protein, His-tagged E.coli His 1-120 aa
Human SETD3-1861HFL Recombinant Full Length Human SETD3 Protein, C-Flag-tagged Mammalian cells Flag
Mouse SETD3-14980M Recombinant Mouse SETD3 Protein Mammalian Cell His
Mouse Setd3-5799M Recombinant Mouse Setd3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SETD3-8068M Recombinant Mouse SETD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SETD3-8068M-B Recombinant Mouse SETD3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SETD3-4163R Recombinant Rhesus monkey SETD3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SETD3-3980R-B Recombinant Rhesus Macaque SETD3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SETD3-3980R Recombinant Rhesus Macaque SETD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish SETD3-10409Z Recombinant Zebrafish SETD3 Mammalian Cell His
Chicken SETD3-1625C Recombinant Chicken SETD3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SETD3 Related Articles

SETD3 involved in several pathways and played different roles in them. We selected most pathways SETD3 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, PKMTs methylate histone lysines, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesCHD4A;PHF8;RUVBL2;SMARCC2;TAF6L;ANO9A;KAT6B;ASH2L;BRD8
Chromatin organizationKDM3A;JMJD6;PADI2;KAT7;MSL2;SMARCA2;CCDC101;KDM5B;ING5A
PKMTs methylate histone lysinesATF7IP;ASH2L;SUZ12A;DPY30;SMYD2;SMYD2A;SMYD3;SUZ12B;SETD3

SETD3 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, histone methyltransferase activity (H3-K36 specific), histone methyltransferase activity (H3-K4 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by SETD3 itself. We selected most functions SETD3 had, and list some proteins which have the same functions with SETD3. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II activating transcription factor bindingNFE2L2;EGR2;HIPK2;EP300;HEY2;JUN;BEX1;SMAD3;LMO2
histone methyltransferase activity (H3-K36 specific)SMYD2A;SETMAR;SETD3;ASH1L;SMYD2;SMYD2B;SETD2;NSD1
histone methyltransferase activity (H3-K4 specific)WHSC1L1;KMT2A;SETMAR;WBP7;SMYD1B;MLL5;MLL1;SETD3;WDR82
transcription coactivator activitySAP130;RB1;SMARCE1;RAP2C;MYCBP;NPAT;KLF7;PRDM16;TAF6L

SETD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD3.

SRPK1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; cona_canen

Elf, K; Sheuchenko, G; et al. Alterations in muscle proteome of patients diagnosed with amyotrophic lateral sclerosis. JOURNAL OF PROTEOMICS 108:55-64(2014).
Fabi, A; Mottolese, M; et al. Therapeutic targeting of ERBB2 in breast cancer: understanding resistance in the laboratory and combating it in the clinic. JOURNAL OF MOLECULAR MEDICINE-JMM 92:681-695(2014).
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