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SETD6

  • Official Full Name

    SET domain containing 6

  • Synonyms

    SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SETD6-200H Active Recombinant Human SETD6 protein, GST-tagged Insect Cell GST
Human SETD6-261H Recombinant Human SETD6 protein, GST-tagged E.coli GST
Human SETD6-1002H Recombinant Human SETD6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SETD6-3582H Recombinant Human SETD6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse SETD6-14983M Recombinant Mouse SETD6 Protein Mammalian Cell His
Mouse Setd6-5800M Recombinant Mouse Setd6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SETD6-8070M-B Recombinant Mouse SETD6 Protein Pre-coupled Magnetic Beads HEK293
Mouse SETD6-8070M Recombinant Mouse SETD6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SETD6-5349R Recombinant Rat SETD6 Protein Mammalian Cell His
Rat SETD6-5008R Recombinant Rat SETD6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SETD6-5008R-B Recombinant Rat SETD6 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SETD6-10003Z Recombinant Zebrafish SETD6 Mammalian Cell His
Chicken SETD6-2277C Recombinant Chicken SETD6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SETD6 Related Articles

SETD6 involved in several pathways and played different roles in them. We selected most pathways SETD6 participated on our site, such as Activation of SMO, Assembly of the primary cilium, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of SMOGAS8;EFCAB7;BOC;EVC;SETD6;KIF3A;EVC2;ADRBK1;CDON
Assembly of the primary ciliumSDCCAG8;ACTR1A;UNC119B;IFT122;MAPRE1A;DYNLL2B;BBS7;DCTN3;KIF17
BBSome-mediated cargo-targeting to ciliumBBS9;CCT8;SSTR3;RAB3IP;CCT4;BBS5;MKKS;BBS2;BBS4
Basal cell carcinomaWNT10B;GLI3;WNT2;TCF7;WNT9A;AXIN1;WNT4;WNT6;TCF7L2
Cargo trafficking to the periciliary membraneBBS9;PKD1;UNC119.1;CCT8;CCT2;ARF4A;EXOC3;UNC119B;ARL13B
Class B/2 (Secretin family receptors)GCGA;CRH;CD97;PTHLHA;GNB3A;EMR2;PTH2;SETD6;RAMP3
GPCR ligand bindingAPLN;GPBAR1;PPY;GPR31;RGS1;CNR1;SCT;CXCR6;NPFF
GPCRs, OtherVMN1R54;GPR61;OR3A4P;GPR176;GPR132;GPR17;SETD6;GPR88;GPR116

SETD6 has several biochemical functions, for example, G-protein coupled receptor activity, NOT Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD6 itself. We selected most functions SETD6 had, and list some proteins which have the same functions with SETD6. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityOR2H1;OR7D2;OLFR497;LPAR2B;TAAR14E;RXFP3.2B;GPR125;OXGR1;OR6K3
NOT Wnt-activated receptor activitySFRP1;FRZB;SFRP1B;SFRP1A;TSPAN12;SFRP4;SFRP2;SMO;SETD6
Wnt-protein bindingSZL;FZD8A;ROR2;FZD2;FZD7A;FZD8B;FZD3B;FZD5;SFRP1A
drug bindingCHKA;RARB;DCK;HMGB2;PPP3CB;PPARG;HMGCS1;GSTP2;CHRNB2
patched bindingCAV1;CCNB1;BBS1;SMO;SETD6;Shh;IHH;PTCH1;DHH
protein bindingMASP1;UBA2;APOOL;SCIMP;MYO6;IPO4;CMTM3;UBAP1;RPF1

SETD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD6.

Ankrd1

Yu, Y; Lasanajak, Y; et al. Human Milk Contains Novel Glycans That Are Potential Decoy Receptors for Neonatal Rotaviruses. MOLECULAR & CELLULAR PROTEOMICS 13:2944-2960(2014).
Back, JW; Frisch, C; et al. Selecting highly structure-specific antibodies using structured synthetic mimics of the cystine knot protein sclerostin. PROTEIN ENGINEERING DESIGN & SELECTION 25:251-259(2012).
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