SGCD
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Official Full Name
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
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Overview
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. -
Synonyms
SGCD; sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); sarcoglycan, delta (35kD dystrophin associated glycoprotein); delta-sarcoglycan; CMD1L; DAGD; LGMD2F; 35 kDa dystrophin associated glycoprotein; 35 kDa dystrophin-associated glycoprotein; 35DAG; Delta-SG; Dystrophin associated glycoprotein delta sarcoglycan; MGC22567; Sarcoglycan delta (35 kDa dystrophin associated glycoprotein); SG delta; SGCD_HUMAN; SGCDP; SGD; OTTHUMP00000223946; OTTHUMP00000223947; OTTHUMP00000223961; placental delta sarcoglycan; 35kD dystrophin-associated glycoprotein; dystrophin associated glycoprotein, delta sarcoglycan; SG-delta;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mesocricetus auratus (Golden hamster)
- Mouse
- Mus musculus (Mouse)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Wheat Germ
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SGCD-7536H | Recombinant Human SGCD, His-tagged | E.coli | His | 57-289aa |
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| Human | SGCD-26997TH | Recombinant Human SGCD | Wheat Germ | N/A | 76 amino acids |
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| Human | SGCD-1888HCL | Recombinant Human SGCD 293 Cell Lysate | HEK293 | N/A |
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| Mouse | SGCD-15030M | Recombinant Mouse SGCD Protein | Mammalian Cell | His |
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| Mouse | SGCD-8097M-B | Recombinant Mouse SGCD Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | SGCD-8097M | Recombinant Mouse SGCD Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mesocricetus auratus (Golden hamster) | RFL34343MF | Recombinant Full Length Mesocricetus Auratus Delta-Sarcoglycan(Sgcd) Protein, His-Tagged | E.coli expression system | His | Full Length (1-289) |
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| Mus musculus (Mouse) | RFL7088MF | Recombinant Full Length Mouse Delta-Sarcoglycan(Sgcd) Protein, His-Tagged | E.coli expression system | His | Full Length (1-289) |
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| Zebrafish | SGCD-231Z | Recombinant Zebrafish SGCD | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- SGCD Related Research Area
SGCD involved in several pathways and played different roles in them. We selected most pathways SGCD participated on our site, such as Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hypertrophic cardiomyopathy (HCM) | MYH7;DAG1;ITGA10;SGCB;TGFB2;ACE;ITGAV;SGCA;TPM2 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ACTN1;ITGB8;CACNB1;ITGA4;CACNB4;CACNA2D2;ITGA10;ITGB6;Itga10&Itgb1 |
| Dilated cardiomyopathy | Itga10&Itgb1;MYH7;ITGB8;TGFB1;CACNG3;CACNB1;GNAS;CACNG4;ITGA9 |
| Viral myocarditis | SGCB;H2-Q10;SGCG;LAMA2;RAC1;HLA-E;HLA-DMA;HLA-DOB;FYN |
SGCD has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SGCD itself. We selected most functions SGCD had, and list some proteins which have the same functions with SGCD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
SGCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGCD here. Most of them are supplied by our site. Hope this information will be useful for your research of SGCD.
FLNC; ADA; SERPINA3
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