SGCG
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Official Full Name
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
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Overview
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). -
Synonyms
SGCG; sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); DMDA1, LGMD2C, MAM, sarcoglycan, gamma (35kD dystrophin associated glycoprotein); gamma-sarcoglycan; 35kD dystrophin associated glycoprotein; A4; DAGA4; DMDA; gamma sarcoglycan; limb girdle muscular dystrophy 2C (Duchenne like muscular dystrophy; autosomal recessive); Maghrebian myopathy (autosomal recessive); MGC130048; SCARMD2; SCG3; TYPE; 35 kDa dystrophin associated glycoprotein; Gamma SG; 35 kDa dystrophin-associated glycoprotein; 35DAG; DMDA1; Gamma-SG; LGMD2C; MAM; Sarcoglycan gamma; SGCG_HUMAN; OTTHUMP00000018112; 35kD dystrophin-associated glycoprotein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mesocricetus auratus (Golden hamster)
- Mouse
- Mus musculus (Mouse)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- Myc
- DDK
- Flag
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | SGCG-28970TH | Recombinant Human SGCG | Wheat Germ | N/A | 291 amino acids | |
Human | SGCG-26403TH | Recombinant Human SGCG | Wheat Germ | N/A | 100 amino acids | |
Human | SGCG-2629H | Recombinant Human SGCG, His-tagged | E.coli | His | 1-291aa | |
Human | SGCG-1887HCL | Recombinant Human SGCG 293 Cell Lysate | HEK293 | N/A | ||
Human | SGCG-1905HFL | Recombinant Full Length Human SGCG Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | SGCG-1996H | Recombinant Human SGCG Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | SGCG-359H | Recombinant Human SGCG Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | C-Myc/DDK | ||
Human | SGCG-469HF | Recombinant Full Length Human SGCG Protein | In Vitro Cell Free System | 291 amino acids | ||
Human | SGCG-1996H-B | Recombinant Human SGCG Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | SGCG-15032M | Recombinant Mouse SGCG Protein | Mammalian Cell | His | ||
Mouse | SGCG-8099M | Recombinant Mouse SGCG Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | SGCG-8099M-B | Recombinant Mouse SGCG Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Sgcg-5822M | Recombinant Mouse Sgcg Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mesocricetus auratus (Golden hamster) | RFL14882MF | Recombinant Full Length Mesocricetus Auratus Gamma-Sarcoglycan(Sgcg) Protein, His-Tagged | E.coli expression system | His | Full Length (1-291) | |
Mus musculus (Mouse) | RFL29667MF | Recombinant Full Length Mouse Gamma-Sarcoglycan(Sgcg) Protein, His-Tagged | E.coli expression system | His | Full Length (1-291) | |
Zebrafish | SGCG-1087Z | Recombinant Zebrafish SGCG | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- SGCG Related Articles
SGCG involved in several pathways and played different roles in them. We selected most pathways SGCG participated on our site, such as Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGCG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Hypertrophic cardiomyopathy (HCM) | CACNA2D1;ITGA7;LMNA;ACTB;CACNB3;PRKAA2;CACNG7;Itga10&Itgb1;TNF |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | SGCA;CACNA2D2;GJA1;ITGB3;JUP;DSC2;ACTN2;ITGB5;DAG1 |
Dilated cardiomyopathy | ITGB7;CACNA2D3;CACNB4;IGF1;ITGB3;PLN;CACNG1;Itga10&Itgb1;TPM2 |
Viral myocarditis | HLA-DMB;CXADR;EIF4G3;HLA-DMA;FYN;CD40LG;HLA-DOB;HLA-B;HLA-G |
SGCG has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SGCG itself. We selected most functions SGCG had, and list some proteins which have the same functions with SGCG. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | AAK1;COG8;ZG16;NTN4;ITGB3;RTN1;RPS20;COX5B;FMNL1 |
SGCG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGCG here. Most of them are supplied by our site. Hope this information will be useful for your research of SGCG.
FLNC; DNAJB6; DYSF; ACO1; PTPN11; ENO1; PSAP; HSPA1A; PYGM; ENO3; CCT6A; MYBPC1; MYBPC2
- Q&As
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