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SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2

  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort
  • Synonyms

    SGK2; serum/glucocorticoid regulated kinase 2; serine/threonine-protein kinase Sgk2; H-SGK2; dJ138B7.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SGK2-224H Unactive Recombinant Human SGK2(S416D)(54-end) Mutation Protein, N-His-tagged Sf21 His 54-end
Human SGK2-659H Recombinant Human Serum/Glucocorticoid Regulated Kinase 2 E.coli N/A
Human SGK2-1842H Recombinant Human SGK2 protein, His & T7-tagged E.coli His/T7 Val40~Pro311 (Accession # Q9HBY8)
Human SGK2-2631H Recombinant Human SGK2, GST-tagged E.coli GST C-term-397aa
Human SGK2-429H Recombinant Human SGK2, GST-tagged, Active Sf9 Insect Cell GST
Human SGK2-1885HCL Recombinant Human SGK2 293 Cell Lysate HEK293 N/A
Human SGK2-3784HF Active Recombinant Full Length Human SGK2 Protein, GST-tagged Insect (sf21) GST 1-367
Human SGK2-1182H Recombinant Human SGK2 Protein (Q2-C427), Tag Free Insect Cell No tag Q2-C427
Human SGK2-2612H Recombinant Human SGK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SGK2-1183H Recombinant Human SGK2 Protein (Q2-C427), GST tagged Insect Cell GST Q2-C427
Human SGK2-5515H Recombinant Human SGK2 Protein (Thr40-Leu311), N-His tagged E.coli N-His Thr40-Leu311
Mouse Sgk2-5825M Recombinant Mouse Sgk2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SGK2-5365R Recombinant Rat SGK2 Protein Mammalian Cell His
Rat SGK2-5024R Recombinant Rat SGK2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SGK2-5024R-B Recombinant Rat SGK2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway, Insulin Signaling, Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FoxO signaling pathwayMAPK14B;KLF2;TGFB3;IGF1RA;IRS1;GADD45G;SGK2;SMAD3;SLC2A4
Insulin SignalingSTXBP3A;MAP3K10;EHD1;RHOJ;STXBP4;MAPK4;MAP3K9;STXBP2;GSK3AB
Ion channel transportTRPC4B;TRPC4APA;CLCN4-2;BEST1;TRPM1;ATP2C1;CLCN5;SLC17A3;WNK1
PI3K-Akt signaling pathwayPIK3AP1;SGK2;CDC37;COMP;CSF3R;CSF1;PRP2;EFNA2;CHAD
Stimuli-sensing channelsSGK2;ANO8;ANO5B;NHEDC1;MCOLN2;TRPC4B;CLCN1;TRPM1;TTYH3
Transmembrane transport of small moleculesADD2;GLRBA;SLC9A3.2;CLCNK;CLCN6;MIPB;SLC6A19B;ANO5;SLC7A11

SGK2 has several biochemical functions, for example, ATP binding, calcium channel regulator activity, chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingLANCL2;GLULC;SGK3;LIG1;DDX3;QARS;CCT8;ADCY9;MYLK2
calcium channel regulator activityNRXN3;NPY;SGK2;CACNB2;CACNA2D1A;SGK1;CACNA2D1;HPCAL4;PRKG1
chloride channel regulator activityBSND;SGK1;SGK2A;CHRNA7;SGK2B;SLC9A3R1;SGK3;SGK2
potassium channel regulator activityYWHAE;ADRB2;PRKCZ;SGK1;DRD4;ARPP19;ANK2;DPP10;KCNAB3
protein serine/threonine kinase activityBUB1B;STK32C;ROCK2B;SRPK3;NEK1;RIOK1;CDK12;ACVRL1;TAOK3
sodium channel regulator activitySGK2B;FXYD3;RANGRF;SGK2;SGK2A;SCLT1;NEDD4L;YWHAH;GPD1L

SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

HSP90AB1; IL3RA; DDX5; TCP1; CCT6A; CCT5; CCT3; CCT8; CCT4; ILF3; FKBP5; CCT7

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