Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SHC3

  • Official Full Name

    SHC (Src homology 2 domain containing) transforming protein 3

  • Overview

    SHC-transforming protein 3 is a protein that in humans is encoded by the SHC3 gene.
  • Synonyms

    SHC3; SHC (Src homology 2 domain containing) transforming protein 3; src homology 2 domain containing transforming protein C3; SHC-transforming protein 3; N Shc; NSHC; SHCC; N-Shc; Neuronal Shc; Protein Rai; Rai; SH2 domain protein C3; SHC protein C; SHC-like protein, neuronal; SHC-transforming protein C; SHC3_HUMAN; Src homology 2 domain-containing transforming protein; Src homology 2 domain-containing-transforming protein C3; src homology 2 domain-containing transforming protein C3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SHC3-2655H Recombinant Human SHC3, GST-tagged E.coli GST C-term-351aa
Human SHC3-1277H Recombinant Human SHC3 protein, His & GST-tagged E.coli His/GST Val188~Gln433 (Accession # Q92529)
Human SHC3-1602HCL Recombinant Human SHC3 cell lysate N/A
Human SHC3-5922H Recombinant Human SHC3 Protein (Val188-Gln433), N-GST tagged E.coli N-GST Val188-Gln433
Mouse SHC3-15092M Recombinant Mouse SHC3 Protein Mammalian Cell His
Mouse SHC3-8143M-B Recombinant Mouse SHC3 Protein Pre-coupled Magnetic Beads HEK293
Mouse SHC3-8143M Recombinant Mouse SHC3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SHC3-4193R Recombinant Rhesus monkey SHC3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SHC3-4009R Recombinant Rhesus Macaque SHC3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SHC3-4009R-B Recombinant Rhesus Macaque SHC3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SHC3 Related Articles
  • SHC3 Related Signal Pathway

SHC3 involved in several pathways and played different roles in them. We selected most pathways SHC3 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayAREGB;PTK2AB;PRKCBB;PAK6;MAPK8A;MAP2K7;ERBB2;ERBB4;MAP2K2B
Ras signaling pathwayPRKCA;FGF12;PRKCG;Fasl;PIK3CG;IGF1;PLA2G4D;TEK;GAB1
Chemokine signaling pathwaySHC2;GM13304;GM13306;RHOA;CXCL6;RELA;Ccl21c;GM10591;CCL11
Phospholipase D signaling pathwayPIK3R1;PTK2B;AVPR2;FYN;RALGDS;PDGFD;PIK3CA;GRM2;MAPK3
Focal adhesionHRASA;PRKCB;PIK3CA;PPP1R12B;ITGA4;COL5A2A;FYNB;STYK1;TNXB
Natural killer cell mediated cytotoxicityMAP2K2;RAET1L;CD244;MAPK1;GZMB;Casp3;BID;PPP3R2;VAV1
Neurotrophin signaling pathwayCALM1;RPS6KA2;FASLG;ABL1;NTF4;KRAS;AKT2;PRDM4;CALM4
Insulin signaling pathwayPRKAR1B;PRKAG2A;MAPK9;FOXO1;HK1;PYGMA;PRKACAB;CALM3;RPS6
Estrogen signaling pathwayKCNJ9;NOS3;FKBP5;HSPA1B;HSPA1L;PLCB4;CALM2;PLCB1;ATF4
Prolactin signaling pathwaySOCS4;PIK3R1;MAPK3;MAPK9;PRLR;PIK3CD;PIK3R3;NEK3;CCND2
AlcoholismHIST1H2AB;H2BFWT;PPP1CA;GM14477;HDAC7A;GRIN2B;HDAC5;GM6026;ARAF
Bacterial invasion of epithelial cellsWASL;SEPT2;PIK3CD;PIK3CG;SRC;PXN;WAS;CLTA;CRK
GliomaPIK3CD;PIK3R2;HRAS;PRKCB;TRP53;PDGFA;PDGFRA;MAPK1;TGFA
Chronic myeloid leukemiaTGFB2;CRKL;AKT2;KRAS;TGFB3;CRK;CDK6;MECOM;CTBP2

SHC3 has several biochemical functions, for example, protein binding, protein kinase binding, receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC3 itself. We selected most functions SHC3 had, and list some proteins which have the same functions with SHC3. You can find most of the proteins on our site.

Function Related Protein
protein bindingDAB1;FBXO5;DZIP3;MLST8;NUAK1;ROCK2;Unc5b;ROR2;FLNA
protein kinase bindingRNF138;FAM83B;SHC3;IL12RB2;NME2;CDKN2A;PGAM1;LLGL1;GYS1
receptor tyrosine kinase bindingANXA5;ANGPT4;ANGPT2A;CPNE3;FIZ1;ANGPT1;MYOC;ELMO2;TOB1
signal transducer activityMIER1B;GPR141;TAS2R110;PTH1RB;FZD1;VMN1R43;FLNA;VMN1R40;SECTM1

SHC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC3.

GOLGA2; KRT31; KRT40; EGFR; ERBB2; MET; AR; KIT; ERBB3; GAB1

Mierzejewska, K; Heo, J; et al. Genome-wide analysis of murine bone marrow-derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 32:281-290(2013).
Adams, SJ; Aydin, IT; et al. GAB2-a Scaffolding Protein in Cancer. MOLECULAR CANCER RESEARCH 10:1265-1270(2012).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SHC3 Products

Required fields are marked with *

My Review for All SHC3 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends