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SHF

Official Full Name

Src homology 2 domain containing F
Overview

Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
Synonyms

MGC126650; MGC126652; SH2 domain-containing adapter protein F; SHF;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SHF-2658H	Recombinant Human SHF, His-tagged	E.coli	His	195-378aa	$319 / 25ug
Human	SHF-4691H	Recombinant Human SHF Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	SHF-15098M	Recombinant Mouse SHF Protein	Mammalian Cell	His		Inquiry
Mouse	SHF-8149M-B	Recombinant Mouse SHF Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SHF-8149M	Recombinant Mouse SHF Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Shf-5860M	Recombinant Mouse Shf Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SHF Related Articles

SHF involved in several pathways and played different roles in them. We selected most pathways SHF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SHF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SHF has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by SHF itself. We selected most functions SHF had, and list some proteins which have the same functions with SHF. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	RTN2A;PSG6;MARVELD2B;FAM185A;CRYGM2D12;CRYBA2A;GM4179;DNAAF3;VPS41

SHF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHF here. Most of them are supplied by our site. Hope this information will be useful for your research of SHF.

Liang, S; Li, HC; et al. Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart. DEVELOPMENT GROWTH & DIFFERENTIATION 56:276-292(2014).

Yang, YP; Li, HR; et al. Second heart field and the development of the outflow tract in human embryonic heart. DEVELOPMENT GROWTH & DIFFERENTIATION 55:359-367(2013).