SHFM1
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Official Full Name
split hand/foot malformation (ectrodactyly) type 1
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Overview
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. -
Synonyms
SHFM1; split hand/foot malformation (ectrodactyly) type 1; SHFD1; 26S proteasome complex subunit DSS1; deleted in split hand/foot 1; DSS1; ECD; SEM1; Shfdg1; SHSF1; Deleted in Split-Hand/Split-Foot 1 region; OTTHUMP00000198236; split hand/foot deleted protein 1; deleted in split-hand/split-foot 1; deleted in split hand/split foot protein 1; split hand/foot malformation type 1 protein;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SHFM1-2659H | Recombinant Human SHFM1, GST-tagged | E.coli | GST | 1-70aa | |
| Human | SHFM1-2440H | Recombinant human SHFM1, His-tagged | E.coli | His |
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| Mouse | SHFM1-15099M | Recombinant Mouse SHFM1 Protein | Mammalian Cell | His |
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| Mouse | SHFM1-8150M | Recombinant Mouse SHFM1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | SHFM1-8150M-B | Recombinant Mouse SHFM1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | SHFM1-4194R | Recombinant Rhesus monkey SHFM1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | SHFM1-4010R | Recombinant Rhesus Macaque SHFM1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | SHFM1-4010R-B | Recombinant Rhesus Macaque SHFM1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | SHFM1-9996Z | Recombinant Zebrafish SHFM1 | Mammalian Cell | His |
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| Chicken | SHFM1-3685C | Recombinant Chicken SHFM1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- SHFM1 Related Articles
SHFM1 involved in several pathways and played different roles in them. We selected most pathways SHFM1 participated on our site, such as Proteasome, Homologous recombination, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHFM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome | PSMB11B;PSME4;PSMC4;PSMA7;PSMB8F;PSMD3;PSMC2;PSME4B;PSMD2 |
| Homologous recombination | RPA4;RPA2;POLD1;BRCA2;RAD51L3;RAD52;TOP3B;MUS81;XRCC2 |
| Epstein-Barr virus infection | CD58;RBPJ;GSK3B;PIK3R3;MDM2;POLR2J;POLR2D;ENTPD3;HSPB1 |
SHFM1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHFM1 itself. We selected most functions SHFM1 had, and list some proteins which have the same functions with SHFM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZNF10;PIP4K2B;DPYSL5;YY1;ATP6V0D1;EYA3;OAS1;RGR;TNS1 |
SHFM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHFM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHFM1.
BRCA2; PSMD3; ADRM1; Brca2; NUDT21; PCID2; MAP1LC3B; PSMD9; UBFD1; TXNL1; MARCH6
- Q&As
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