SIK2
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Official Full Name
salt-inducible kinase 2
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Overview
SIK2 (Salt inducible kinase 2) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and AMP-activated protein kinase (AMPK) subfamily, predicted molecular weight 104 kD. SIK2 is found in adipocytes and might be involved in metabo -
Synonyms
SIK2; salt-inducible kinase 2; SNF1 like kinase 2 , SNF1LK2; serine/threonine-protein kinase SIK2; DKFZp434K1115; KIAA0781; LOH11CR1I; QIK; SIK-2; SNF1-like kinase 2; qin-induced kinase; salt-inducible protein kinase 2; salt-inducible serine/threonine kin;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Sf21
- Sf9 Insect Cell
- GST
- His|T7
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SIK2-1478H | Active Recombinant Human QIK, GST-tagged | Sf9 Insect Cell | GST | Full length |
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| Human | SIK2-228H | Active Recombinant Human SIK2(1-276) Protein, N-GST-tagged | Sf21 | GST | 1-276 aa |
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| Human | SIK2-30089TH | Recombinant Human SIK2 | N/A |
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| Human | SIK2-415H | Recombinant Human Salt-inducible Kinase 2, GST-tagged, Active | Sf9 Insect Cell | GST |
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| Human | SIK2-1841HCL | Recombinant Human SIK2 293 Cell Lysate | HEK293 | N/A |
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| Human | SIK2-1954H | Recombinant Human SIK2 protein, His & T7-tagged | E.coli | His/T7 | Gln655~Val925 (Accession # Q9H0K1) |
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| Human | SIK2-3156H | Recombinant Human SIK2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Mouse | Sik2-1955M | Recombinant Mouse Sik2 protein, His & T7-tagged | E.coli | His/T7 | Ser674~Val916 (Accession # Q8CFH6) |
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| Mouse | Sik2-5878M | Recombinant Mouse Sik2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
- SIK2 Related Signal Pathway
SIK2 involved in several pathways and played different roles in them. We selected most pathways SIK2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SIK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
SIK2 has several biochemical functions, for example, ATP binding, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIK2 itself. We selected most functions SIK2 had, and list some proteins which have the same functions with SIK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DHX32A;NADKD1;SPHK1;CDC7;FLT1;ATP1A1A.3;DDX47;HSPA14;TTLL3 |
| magnesium ion binding | ENOSF1;CIB4;PSPH;CIB3;PPA1B;STK36;PRPSAP1;STK38L;ENO1B |
| protein binding | AZIN1;CRY2;ASH2L;AHSP;DLGAP1;TEKT5;TXLNB;VTN;PAWR |
| protein serine/threonine kinase activity | NEK5;ADCK5;MAP3K4;MAPK4;PKZ;BCKDK;ROCK1;EIF2AK3;MAP3K10 |
SIK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIK2.
CEP250; GABARAPL2; PPP2R2B; linkable pd173955 analogue; bosutinib; imatinib; dasatinib; midostaurin; BAG2; HSPB1; PPP2R1B; FUS
- Q&As
- Reviews
Q&As (5)
Ask a questionPotential side effects may include metabolic disturbances, immune system dysregulation, and off-target effects on other cellular processes.
Researchers are exploring the potential of SIK2 inhibitors as a novel treatment approach for various diseases, including diabetes, cancer, and inflammatory disorders.
SIK2 regulates the function of immune cells, including T cells and macrophages, and targeting SIK2 may modulate immune responses in autoimmune and inflammatory diseases.
Yes, mutations in the SIK2 gene have been linked to certain rare genetic disorders that affect metabolism and cellular signaling pathways.
Yes, SIK2 has been identified as a potential target for the development of novel anti-inflammatory drugs due to its role in regulating immune responses.
Customer Reviews (3)
Write a reviewI highly recommend the SIK2 Protein for its outstanding performance in ELISA assays.
It has been extensively used in protein-protein interaction studies, enzymatic assays, and structural analyses, showcasing its reliability and adaptability in diverse research areas.
I am certain of obtaining reliable and reproducible results, enabling me to contribute to scientific progress and make new discoveries.
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