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SIN3B

Official Full Name

SIN3 transcription regulator homolog B
Overview

Paired amphipathic helix protein Sin3b is a protein that in humans is encoded by the SIN3B gene.
Synonyms

SIN3B; SIN3 transcription regulator homolog B (yeast); SIN3 homolog B, transcription regulator (yeast); paired amphipathic helix protein Sin3b; KIAA0700; transcriptional corepressor Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcrip;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SIN3B-1606HCL	Recombinant Human SIN3B cell lysate		N/A		Inquiry
Zebrafish	SIN3B-4043Z	Recombinant Zebrafish SIN3B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SIN3B Related Articles

SIN3B involved in several pathways and played different roles in them. We selected most pathways SIN3B participated on our site, such as Epigenetic regulation of gene expression, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIN3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Epigenetic regulation of gene expression	DNMT1;TAF1D;TAF1C;EED;SAP30BP;SAP30;DNMT3A;DNMT3L;BAZ2A
Fatty acid, triacylglycerol, and ketone body metabolism	TIAM2;ELOVL1A;ACOT11B;PPARGC1B;MTF1;SLC25A1A;MED22;ECI1;GRHL1
Gene Expression	ZNF333;SUPT5H;ZNF697;ZNF713;NR2E1;CSTF3;GTF3AA;ADAT3;MED16
Hedgehog signaling events mediated by Gli proteins	SAP18;KIF3A;CSNK1G3;SPOP;LGALS3;MTSS1;SIN3B;SAP30;CSNK1G2
Metabolism	DPEP1;UGT1B5;B3GNT1;SACM1L;MED8;ECI1;GPC5A;TPH2;MED20
Metabolism of lipids and lipoproteins	CDK19;APOF;AKR1C2;CHKA;ACAD11;DECR1;TIAM2;PPP1R2;ALOX5AP
Negative epigenetic regulation of rRNA expression	SUDS3;TAF1D;TAF1C;SAP130;RRP8;SIN3B;DNMT3B;SAP18;TAF1A
NoRC negatively regulates rRNA expression	CD3EAP;TAF1A;DNMT1;SAP30L;SUDS3;EFCAB11;DNMT3B;SIN3B;BAZ2A

SIN3B has several biochemical functions, for example, RNA polymerase II transcription corepressor activity, chromatin binding, contributes_to histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SIN3B itself. We selected most functions SIN3B had, and list some proteins which have the same functions with SIN3B. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II transcription corepressor activity	UXT;RBBP8;TFAP2B;SIN3B;SIN3A;SOX3;HDAC1;RERE;N4BP2L2
chromatin binding	SSBP1;ATOH1A;KLF14;ZGLP1;NFIA;NAP1L2;NCAPD3;NEUROG1;TRIM24
contributes_to histone deacetylase activity	SIN3AA;BRMS1;BRMS1L;SIN3B;SIN3A;SALL1;SUDS3;BRMS1LA
protein binding	MSX2;PTPRN;RIBC2;NDUFB11;SEPHS1;TUBA1C;HELLS;RNF5;AIP

SIN3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIN3B here. Most of them are supplied by our site. Hope this information will be useful for your research of SIN3B.

HDAC1; MYC; HDAC2; HCFC1; MXD1; PPP1CC; collagen sequence; mdm2_human_probe; pyr1_human_gene; hes1_human_gene; NCL

Nishibuchi, G; Shibata, Y; et al. Physical and Functional Interactions between the Histone H3K4 Demethylase KDM5A and the Nucleosome Remodeling and Deacetylase (NuRD) Complex. JOURNAL OF BIOLOGICAL CHEMISTRY 289:28956-28970(2014).

Li, YL; Choi, PS; et al. MYC through miR-17-92 Suppresses Specific Target Genes to Maintain Survival, Autonomous Proliferation, and a Neoplastic State. CANCER CELL 26:262-272(2014).