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SLBP

  • Official Full Name

    stem-loop binding protein

  • Overview

    The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3' end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle,Increasing more than 10-fold during the latter part of G1.
  • Synonyms

    SLBP; stem-loop binding protein; stem loop (histone) binding protein; histone RNA hairpin-binding protein; HBP; histone binding protein; hairpin binding protein, histone; histone stem-loop binding protein; histone stem-loop-binding protein; stem-loop (histone) binding protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • C
  • Myc
  • DDK
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLBP-7795H Recombinant Human SLBP, His-tagged HEK293 His
Human SLBP-596HCL Recombinant Human SLBP lysate HEK293 N/A
Human SLBP-01H Recombinant Human SLBP Protein, C-Myc/DDK-tagged HEK293T C-Myc/DDK
Mouse SLBP-15198M Recombinant Mouse SLBP Protein Mammalian Cell His
Mouse SLBP-8209M-B Recombinant Mouse SLBP Protein Pre-coupled Magnetic Beads HEK293
Mouse SLBP-8209M Recombinant Mouse SLBP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Slbp-5901M Recombinant Mouse Slbp Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish SLBP-8123Z Recombinant Zebrafish SLBP Mammalian Cell His
Zebrafish SLBP-8124Z Recombinant Zebrafish SLBP Mammalian Cell His
Chicken SLBP-1221C Recombinant Chicken SLBP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLBP involved in several pathways and played different roles in them. We selected most pathways SLBP participated on our site, such as Cleavage of Growing Transcript in the Termination Region, Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cleavage of Growing Transcript in the Termination RegionNUDT21;CSTF2;THOC4;U2AF2;SLBP;ZFP473;RNPS1;SRSF11;CSTF3
Gene ExpressionMBD3;ZNF334;NR1I2;HNRNPA0L;ZNF433;ELAVL1;JARID2B;CCNT2A;ZNF10
Processing of Capped Intron-Containing Pre-mRNAPTBP1A;HNRNPA0;HNRNPD;RNPC3;SNRNP25;PTBP1B;HNRNPA0B;RNPS1;HNRPL
Processing of Capped Intronless Pre-mRNAZNF473;NUDT21;CLP1;SLBP;CSTF1;LSM10;CSTF3;LSM11;CSTF2
RNA Polymerase II TranscriptionTHOC4;SLBP;ZNF473;CSTF2;CSTF3;LSM10;ZFP473;SRSF11;CCNT2A
RNA Polymerase II Transcription TerminationNUDT21;U2AF2;CSTF3;ZNF473;LSM10;CLP1;SLBP;SRSF11;PAPOLA
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAsSLBP;LSM10;ZFP473;LSM11;ZNF473
Transport of Mature Transcript to CytoplasmU2AF2;SLBP;SRSF11;NXF1;SFRS3A

SLBP has several biochemical functions, for example, histone pre-mRNA DCP binding, histone pre-mRNA stem-loop binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLBP itself. We selected most functions SLBP had, and list some proteins which have the same functions with SLBP. You can find most of the proteins on our site.

Function Related Protein
histone pre-mRNA DCP bindingSLBP;SNRPD3;SNRPB;LSM10
histone pre-mRNA stem-loop bindingERI1;SLBP
mRNA bindingRC3H2;IGF2BP2A;TYMS;ADARB1;RBM4;PAIP2;RBM8A;IGF2BP1;PURB
poly(A) RNA bindingDDX42;PUM1;USP10;DCN;RPL6;SRP54A;FASTKD2;ERI3;C1orf131
protein bindingMCCC2;ATP6V1H;USP6;AHSA1;ZSCAN12;GAS6;CGGBP1;SATB1;TXNDC11

SLBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLBP here. Most of them are supplied by our site. Hope this information will be useful for your research of SLBP.

CDK4; CDK6; stem_loop_rna; ZNF473; TACC3

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