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SLC15A1

Official Full Name

solute carrier family 15 (oligopeptide transporter), member 1
Overview

This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.
Synonyms

SLC15A1; solute carrier family 15 (oligopeptide transporter), member 1; solute carrier family 15 member 1; bA551M18.1.1 (solute carrier family 15 (oligopeptide transporter) member 1); HPECT1; HPEPT1; PEPT1; peptide transporter HPEPT1; solute carrier family 15 oligopeptide transporter member 1; small intestine isoform; +peptide cotransporter; Human peptide transporter (HPEPT1) mRNA complete cds; Intestinal H; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter; Oligopeptide transporter small intestine isoform; Peptide transporter 1; S15A1_HUMAN; Solute carrier family 15 (oligopeptide transporter) member 1; OTTHUMP00000018599; Caco-2 oligopeptide transporter; intestinal H+/peptide cotransporter; macrophage oligopeptide transporter PEPT1; oligopeptide transporter, small intestine isoform;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian cell
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
His|T7
N/A
Strep

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC15A1-30924TH	Recombinant Human SLC15A1	Wheat Germ	N/A	100 amino acids	Inquiry
Human	SLC15A1-1209H	Recombinant Human SLC15A1 protein, His & T7-tagged	E.coli	His/T7	Asp383~Gln584 (Accession # P46059)	Inquiry
Human	SLC15A1-0915H	Recombinant Human SLC15A1 Protein (G2-M708), Strep/His tagged	Mammalian cell	Strep/His	G2-M708	Inquiry
Rat	SLC15A1-5434R	Recombinant Rat SLC15A1 Protein	Mammalian Cell	His		Inquiry
Rat	SLC15A1-5093R	Recombinant Rat SLC15A1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SLC15A1-5093R-B	Recombinant Rat SLC15A1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	SLC15A1-4221R	Recombinant Rhesus monkey SLC15A1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SLC15A1-4037R	Recombinant Rhesus Macaque SLC15A1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	SLC15A1-4037R-B	Recombinant Rhesus Macaque SLC15A1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	SLC15A1-8527Z	Recombinant Zebrafish SLC15A1	Mammalian Cell	His		Inquiry
Chicken	SLC15A1-5936C	Recombinant Chicken SLC15A1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC15A1 involved in several pathways and played different roles in them. We selected most pathways SLC15A1 participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC15A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Protein digestion and absorption	PRSS1;SLC8A2;CELA2B;PGA4;CELA2A;ATP1A4;PRSS3;FXYD2;COL18A1

SLC15A1 has several biochemical functions, for example, peptide:proton symporter activity, proton-dependent oligopeptide secondary active transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC15A1 itself. We selected most functions SLC15A1 had, and list some proteins which have the same functions with SLC15A1. You can find most of the proteins on our site.

Function	Related Protein
peptide:proton symporter activity
proton-dependent oligopeptide secondary active transmembrane transporter activity	SLC15A1;CDH17

SLC15A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC15A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC15A1.