Background
The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small;peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This;transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter;found in the small intestine (Liu et al, 1995 (PubMed 7756356)).