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SLC17A5

Official Full Name

solute carrier family 17 (anion/sugar transporter), member 5
Overview

This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form.
Synonyms

SLC17A5; solute carrier family 17 (anion/sugar transporter), member 5; sialic acid storage disease , SIASD; sialin; AST; ISSD; NSD; SD; SLD; Membrane glycoprotein HP59; S17A5_HUMAN; Sialic acid storage disease; Sodium/sialic acid cotransporter; Solute carrier family 17; Solute carrier family 17 member 5; OTTHUMP00000016747; solute carrier family 17, member 5; SIASD;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
His|T7
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC17A5-1206H	Recombinant Human SLC17A5 protein, His & T7-tagged	E.coli	His/T7	Thr146~Phe405 (Accession # Q9NRA2)	Inquiry
Human	SLC17A5-5799H	Recombinant Human SLC17A5 Protein (Thr146-Phe405), N-His tagged	E.coli	N-His	Thr146-Phe405	Inquiry
Mouse	SLC17A5-15244M	Recombinant Mouse SLC17A5 Protein	Mammalian Cell	His		Inquiry
Mouse	SLC17A5-8242M	Recombinant Mouse SLC17A5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SLC17A5-8242M-B	Recombinant Mouse SLC17A5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	SLC17A5-4226R	Recombinant Rhesus monkey SLC17A5 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SLC17A5-4042R	Recombinant Rhesus Macaque SLC17A5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	SLC17A5-4042R-B	Recombinant Rhesus Macaque SLC17A5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	SLC17A5-4567Z	Recombinant Zebrafish SLC17A5	Mammalian Cell	His		Inquiry
Chicken	SLC17A5-2761C	Recombinant Chicken SLC17A5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC17A5 involved in several pathways and played different roles in them. We selected most pathways SLC17A5 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC17A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Lysosome	CLN5;ATP6V0D2;NPC1;CTSW;AP3B2;GGA2;NPC2;CTSSA;ARSG

SLC17A5 has several biochemical functions, for example, sialic acid transmembrane transporter activity, symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC17A5 itself. We selected most functions SLC17A5 had, and list some proteins which have the same functions with SLC17A5. You can find most of the proteins on our site.

Function	Related Protein
sialic acid transmembrane transporter activity
symporter activity	SLC1A3B;SLC16A9;SLC25A3;MFSD2A;SLC24A4;SLC17A5;SLC34A2;SLC20A1B;SLC6A1A

SLC17A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC17A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC17A5.