Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SLC1A1

  • Official Full Name

    solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

  • Overview

    This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
  • Synonyms

    SLC1A1; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; excitatory amino acid transporter 3; EAAC1; EAAT3; excitatory amino acid carrier 1; solute carrier family 1 member 1; neuronal and epithelial;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • 8His
  • MBP,Flag
  • Strep,Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC1A1-2703H Recombinant Human SLC1A1, GST-tagged E.coli GST 430-524aa
Human SLC1A1-1194H Recombinant Human SLC1A1 protein, His & T7-tagged E.coli His/T7 Ser115~Gly209 (Accession # P43005)
Human SLC1A1-1212H Recombinant Human SLC1A1 Protein (G2-F524), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag G2-F524
Human SLC1A1-1211H Recombinant Human SLC1A1 Protein (G2-F524), 8×His-Strep, Flag tagged Insect Cell 8His-Strep,Flag G2-F524
Human SLC1A1-6298H Recombinant Human SLC1A1 Protein (Ser115-Gly209), N-His tagged E.coli N-His Ser115-Gly209
Mouse SLC1A1-15252M Recombinant Mouse SLC1A1 Protein Mammalian Cell His
Mouse SLC1A1-8248M Recombinant Mouse SLC1A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SLC1A1-8248M-B Recombinant Mouse SLC1A1 Protein Pre-coupled Magnetic Beads HEK293
Rat SLC1A1-5446R Recombinant Rat SLC1A1 Protein Mammalian Cell His
Rat SLC1A1-5105R-B Recombinant Rat SLC1A1 Protein Pre-coupled Magnetic Beads HEK293
Rat SLC1A1-5105R Recombinant Rat SLC1A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLC1A1-4229R Recombinant Rhesus monkey SLC1A1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLC1A1-4045R Recombinant Rhesus Macaque SLC1A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLC1A1-4045R-B Recombinant Rhesus Macaque SLC1A1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SLC1A1-775Z Recombinant Zebrafish SLC1A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC1A1 Related Articles

SLC1A1 involved in several pathways and played different roles in them. We selected most pathways SLC1A1 participated on our site, such as Glutamatergic synapse, Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC1A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutamatergic synapsePRKACG;GRIN2A;SHANK3;Adcy4;GRM4;PLA2G4A;GNAI3;GRIN3B;GNB3
Protein digestion and absorptionXPNPEP2;SLC8A2;MEP1A;COL18A1;CPA2;KCNE3;ATP1B1;FXYD2;KCNJ13

SLC1A1 has several biochemical functions, for example, L-glutamate transmembrane transporter activity, cysteine transmembrane transporter activity, glutamate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC1A1 itself. We selected most functions SLC1A1 had, and list some proteins which have the same functions with SLC1A1. You can find most of the proteins on our site.

Function Related Protein
L-glutamate transmembrane transporter activitySLC1A7;SLC17A6;SLC17A6A;SLC17A6B;SLC17A8;SLC25A22;SLC38A7;SLC25A12;SLC1A6
cysteine transmembrane transporter activity
glutamate bindingSLC1A1;GRIN1;GRM7;CPS1;GRIK1;GLUL;GRIN2A;GAD2;SLC1A3
glutamate:sodium symporter activitySLC1A1;SLC1A2
protein bindingCIDEB;CASP7;BBC3;RHBDL1;MOV10;SCARA3;MON1B;TMEM86B;FAM156A
sodium:dicarboxylate symporter activitySLC13A3;SLC1A2A;SLC1A7A;SLC1A9;SLC1A5;SLC1A3A;SLC1A4;SLC1A7B;SLC13A5

SLC1A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC1A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC1A1.

LDLRAD1; RNF5; EWSR1

Li, YC; Zhou, Y; et al. The Rates of Postmortem Proteolysis of Glutamate Transporters Differ Dramatically between Cells and between Transporter Subtypes. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 60:811-821(2012).
Holmseth, S; Zhou, Y; et al. Specificity Controls for Immunocytochemistry: The Antigen Preadsorption Test Can Lead to Inaccurate Assessment of Antibody Specificity. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 60:174-187(2012).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SLC1A1 Products

Required fields are marked with *

My Review for All SLC1A1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends