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SLC1A4

  • Official Full Name

    solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

  • Overview

    SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine. SLC1A4 mediates the efflux of glutamate from the neuron into the synapt
  • Synonyms

    SLC1A4; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; neutral amino acid transporter A; solute carrier family 1 member 4; alanine/serine/cysteine/threonine transporter 1; SATT; ASCT1; ASCT-1; AW045657;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • 8His
  • MBP,Flag
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC1A4-2705H Recombinant Human SLC1A4, His-tagged E.coli His 431-532aa
Human SLC1A4-1798HCL Recombinant Human SLC1A4 293 Cell Lysate HEK293 N/A
Human SLC1A4-3761H Recombinant Human SLC1A4 protein, GST-tagged E.coli GST 431-532 aa
Human SLC1A4-1294H Recombinant Human SLC1A4 Protein (E2-L532), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag E2-L532
Human SLC1A4-5294H Recombinant Human SLC1A4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SLC1A4-2024H Recombinant Human SLC1A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SLC1A4-1704HFL Recombinant Full Length Human SLC1A4 Protein, C-Flag-tagged Mammalian cells Flag
Human SLC1A4-2024H-B Recombinant Human SLC1A4 Protein Pre-coupled Magnetic Beads HEK293
Mouse SLC1A4-15255M Recombinant Mouse SLC1A4 Protein Mammalian Cell His
Mouse Slc1a4-5909M Recombinant Mouse Slc1a4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SLC1A4-8251M Recombinant Mouse SLC1A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SLC1A4-8251M-B Recombinant Mouse SLC1A4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SLC1A4-637Z Recombinant Zebrafish SLC1A4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC1A4 Related Articles

SLC1A4 involved in several pathways and played different roles in them. We selected most pathways SLC1A4 participated on our site, such as Amino acid transport across the plasma membrane, SLC-mediated transmembrane transport, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC1A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino acid transport across the plasma membraneSLC7A10;SLC38A3A;SLC7A8A;SLC36A2;SLC6A19A;SLC1A4;SLC7A6;SLC3A2B;SLC38A3
SLC-mediated transmembrane transportSLC9A8;SLC7A8A;SLC24A5;SLC6A15;SLC4A3;LCN9;SLC22A15;SLC39A14;RHCG2A
Transmembrane transport of small moleculesTFR1B;SLC2A15A;FKBP1B;SLC6A20B;AQP9B;SLC4A1A;ANO10A;SLC6A11;ATP13A5
Transport of inorganic cations/anions and amino acids/oligopeptidesSLC6A19B;SLC12A1;SLC12A4;SLC1A7A;SLC15A1B;SLC20A1B;SLC7A3;SLC43A1A;SLC17A7A

SLC1A4 has several biochemical functions, for example, L-alanine transmembrane transporter activity, L-cystine transmembrane transporter activity, NOT L-cystine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC1A4 itself. We selected most functions SLC1A4 had, and list some proteins which have the same functions with SLC1A4. You can find most of the proteins on our site.

Function Related Protein
L-alanine transmembrane transporter activitySLC38A7;SLC36A1;SLC36A4;SLC36A2;SLC1A4;SLC38A3;SLC36A3
L-cystine transmembrane transporter activitySLC1A4;CTNS;SLC3A1
NOT L-cystine transmembrane transporter activity
L-glutamine transmembrane transporter activitySLC38A7;SLC38A1;SLC1A5;SLC38A3;SLC1A4
L-hydroxyproline transmembrane transporter activity
L-proline transmembrane transporter activitySLC6A20A;SLC36A3;SLC1A4;SLC6A7;SLC36A1;SLC36A2;SLC36A4
L-serine transmembrane transporter activitySLC38A7;SERINC1;SLC7A10;SERINC4;SLC1A4;SERINC3
L-threonine transmembrane transporter activity
chloride channel activityGABRA4;SLC26A7;CFTR;SLC26A4;BEST1;CLCN3;GABRP;ANO2;SLC26A3.1
sodium:dicarboxylate symporter activitySLC13A5A;SLC1A7B;SLC1A2;SLC1A7;SLC1A2B;SLC1A3;SLC1A3B;SLC1A5;SLC1A9

SLC1A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC1A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC1A4.

Jiang, YX; Ma, Y; et al. Transcriptome and Coexpression Network Analysis of the Human Glioma Cell Line Hs683 Exposed to Candoxin. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 40:887-898(2012).
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