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SLC24A5

Official Full Name

solute carrier family 24, member 5
Overview

This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation.
Synonyms

SLC24A5; solute carrier family 24, member 5; sodium/potassium/calcium exchanger 5; JSX; Ion transporter JSX; NCKX5; Solute carrier family 24 (sodium/potassium/calcium exchanger),member 5; Solute carrier family 24,member 5; Na(+)/K(+)/Ca(2+)-exchange protein 5; solute carrier family 24 (sodium/potassium/calcium exchanger), member 5; SHEP4;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SLC24A5-1788HCL	Recombinant Human SLC24A5 293 Cell Lysate	HEK293	N/A	Inquiry
Zebrafish	SLC24A5-3356Z	Recombinant Zebrafish SLC24A5	Mammalian Cell	His	Inquiry
Chicken	SLC24A5-3312C	Recombinant Chicken SLC24A5	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC24A5 Related Articles

SLC24A5 involved in several pathways and played different roles in them. We selected most pathways SLC24A5 participated on our site, such as SLC-mediated transmembrane transport, Sodium/Calcium exchangers, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC24A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SLC-mediated transmembrane transport	SLC5A11;SLC7A8A;SLC8A2A;SLC10A6;SLC2A13B;SLC1A3A;SLC35B3;SLC2A13;SLC6A20A
Sodium/Calcium exchangers	SLC24A4A;SLC8A2A;SLC24A6;SLC24A5
Transmembrane transport of small molecules	ABCB8;SLC2A15A;SLC1A2A;SLC2A13;CLCN2;SLC26A3.2;MATE4;AQP1A.1;SLC44A5B
Transport of inorganic cations/anions and amino acids/oligopeptides	SLC24A5;SLC36A2;SLC9A5;SLC9A3.1;SLC15A2;SLC17A1;SLC4A3;SLC43A1A;SLC7A3A

SLC24A5 has several biochemical functions, for example, calcium channel activity, calcium ion binding, calcium, potassium:sodium antiporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC24A5 itself. We selected most functions SLC24A5 had, and list some proteins which have the same functions with SLC24A5. You can find most of the proteins on our site.

Function	Related Protein
calcium channel activity	SLC24A5;GPM6A;CACNA1DA;TRPM1;CACNA1BA;TRPV5;TRPM2;TRPV2;TPCN1
calcium ion binding	PLCD4;RASGRP2;FAM20C;NCALDA;LCP1;MMP1;CALRL2;PCDHGA10;MASP2
calcium, potassium:sodium antiporter activity	SLC24A4A;SLC24A1;SLC24A5;SLC24A4;SLC24A2
potassium ion binding	ATP1A1;HDAC4;SLC24A2;SLC24A4;PKLR;PKMB;KCNJ11;PDXK;PKM
sodium ion binding	PDXK;ATP1A1;SLC24A4;CAPN3;SLC34A2;SLC24A5;SCN9A;SLC24A4A;SLC24A2
symporter activity	SLC5A4;SLC16A4;SLC24A2;SLC24A1;SLC38A4;SLC34A2;SLC15A3;SLC16A12;SLC6A1B

SLC24A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC24A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC24A5.

You, JW; Wang, L; et al. Low glucose transporter SLC2A5-inhibited human normal adjacent lung adenocarcinoma cytoplasmic pro-B cell development mechanism network. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:71-76(2015).

Dickinson, H; Ireland, ZJ; et al. Maternal Dietary Creatine Supplementation Does Not Alter the Capacity for Creatine Synthesis in the Newborn Spiny Mouse. REPRODUCTIVE SCIENCES 20:1096-1102(2013).