SLC25A15
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Official Full Name
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
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Overview
This gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome. -
Synonyms
SLC25A15; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; HHH, ORNT1; mitochondrial ornithine transporter 1; D13S327; ORC1; ornithine transporter 1; ORNT1; Solute carrier family 25 member 15; HHH; Ornithine transporter, mitochondrial; ORNT1_HUMAN;
- Recombinant Proteins
- Chicken
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- E.coli
- E.coli expression system
- Insect Cell
- Mammalian Cell
- 8His
- MBP,Flag
- GST
- His
- N
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
- SLC25A15 Related Articles
SLC25A15 involved in several pathways and played different roles in them. We selected most pathways SLC25A15 participated on our site, such as Metabolism, Metabolism of amino acids and derivatives, Metabolism of polyamines, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | ACOT10;LMF2;KCNS3;ANKRD1;IDO2;SLC6A12;CPOX;MAPK1IP1L;SGMS2 |
| Metabolism of amino acids and derivatives | LSM1;AMD2;ACMSD;AMDHD1;CKM;AHCY;CKMT2;HIBADHA;TPH2 |
| Metabolism of polyamines | AZIN1B;CKMB;OAZ1;OAZ2;SLC6A8;CKM;PAOX;SAT1B;NQO1 |
| Urea cycle | SLC25A2;SLC25A15;SLC25A15B;SLC25A15A;NAGS |
SLC25A15 has several biochemical functions, for example, L-ornithine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A15 itself. We selected most functions SLC25A15 had, and list some proteins which have the same functions with SLC25A15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| L-ornithine transmembrane transporter activity | SLC7A1;SLC7A3A;SLC7A4;SLC7A3;SLC25A15 |
SLC25A15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A15 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A15.
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