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SLC26A3

Official Full Name

solute carrier family 26, member 3
Overview

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.
Synonyms

SLC26A3; solute carrier family 26, member 3; CLD, congenital chloride diarrhea , DRA; chloride anion exchanger; down-regulated in adenoma protein; CLD; DRA;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC26A3-2733H	Recombinant Human SLC26A3, GST-tagged	E.coli	GST	C-term-268aaaa	$319 / 25ug
Human	SLC26A3-31415TH	Recombinant Human SLC26A3	Wheat Germ	N/A	98 amino acids	Inquiry
Human	SLC26A3-1753HCL	Recombinant Human SLC26A3 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	SLC26A3-15341M	Recombinant Mouse SLC26A3 Protein	Mammalian Cell	His		Inquiry
Mouse	SLC26A3-8300M	Recombinant Mouse SLC26A3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SLC26A3-8300M-B	Recombinant Mouse SLC26A3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	SLC26A3-5484R	Recombinant Rat SLC26A3 Protein	Mammalian Cell	His		Inquiry
Rat	SLC26A3-5143R	Recombinant Rat SLC26A3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SLC26A3-5143R-B	Recombinant Rat SLC26A3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	SLC26A3-4310C	Recombinant Chicken SLC26A3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC26A3 involved in several pathways and played different roles in them. We selected most pathways SLC26A3 participated on our site, such as Mineral absorption, Multifunctional anion exchangers, Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC26A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mineral absorption	ATOX1;ATP2B1;FXYD2;MT1E;MT1G;SLC30A1;FTL;MT1B;ATP1B2
Multifunctional anion exchangers	SLC26A1;SLC26A3.1;SLC26A7;SLC26A2;SLC26A6L;SLC26A3.2;SLC26A3
Pancreatic secretion	ATP2A1;SCTR;RAP1A;ATP1B4;RHOA;CPB2;RAP1B;TRPC1;CLCA2
SLC-mediated transmembrane transport	SLC7A3A;SLC4A2A;SLC3A2A;SLC6A19A;SLC30A2;SLC28A1;SLC9A6A;SLC26A3.2;PDZD11
Transmembrane transport of small molecules	TTYH3B;SLC4A1A;TRPM4A;SLC43A1A;ANO10;SLC1A7B;SLC28A3;GSDMA2;RHCG2A
Transport of inorganic cations/anions and amino acids/oligopeptides	SLC6A20B;SLC17A1;SLC15A3;SLC20A1B;SLC36A2;SLC15A1B;SLC43A2;SLC43A1B;SLC7A3A

SLC26A3 has several biochemical functions, for example, anion:anion antiporter activity, bicarbonate transmembrane transporter activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC26A3 itself. We selected most functions SLC26A3 had, and list some proteins which have the same functions with SLC26A3. You can find most of the proteins on our site.

Function	Related Protein
anion:anion antiporter activity	Slc4a2;SLC26A2;SLC26A3;SLC26A11;SLC4A11;SLC26A7;SLC26A6;SLC26A4;SLC26A3.2
bicarbonate transmembrane transporter activity	CFTR;SLC26A11;SLC26A6;SLC26A5;SLC26A9;SLC26A1;SLC26A2;SLC26A4;SLC4A11
chloride channel activity	CLIC6;CLCA2;SLC26A3.1;GABRA1;GABRE;CLCN7;APOL1;CLIC5A;CLCN5
chloride transmembrane transporter activity	SLC26A3;SLC26A1;SLC4A1;SLC26A6;Slc4a2;CFTR;SLC26A4
oxalate transmembrane transporter activity	SLC26A4;SLC26A5;SLC26A11;SLC26A3.2;SLC26A3.1;SLC26A6;SLC26A7;SLC26A3;SLC26A1
protein binding	FKBP3;STK11;MSI2;CBLB;CHIC2;BRD4;NFATC4;SOX14;ADAM23
secondary active sulfate transmembrane transporter activity	SLC13A1;SLC26A4;SLC26A3.2;SLC26A11;SLC26A5;SLC26A3.1;SLC26A6L;SLC26A2;SLC26A3
sulfate transmembrane transporter activity	SLC26A6L;SLC26A6;SLC26A2;SLC26A3.1;SLC26A7;SLC26A3;SLC26A4;SLC26A11;SLC26A1
transcription cofactor activity	MED16;MED14;MED4;PRKCBP1L;TAF13;RFXANK;ZFP710;TMF1;THRAP3
transcription factor activity, sequence-specific DNA binding	SALL1;ZNF583;PITX2;CREM;STAT6;ATF7A;SIM1;NPAS1;NR5A1A
transporter activity	SLC12A10.3;RASSF9;AQP8A.2;SLC12A3;ABCA1B;AQP12B;NUP88;SLC23A2;RBP2

SLC26A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC26A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC26A3.

SLC9A3R2