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SLC34A3

Official Full Name

solute carrier family 34 (sodium phosphate), member 3
Overview

This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5 UTR have been found for this gene.
Synonyms

SLC34A3; solute carrier family 34 (sodium phosphate), member 3; sodium-dependent phosphate transport protein 2C; FLJ38680; NPTIIc; naPi-2c; Na(+)/Pi cotransporter 2C; type IIc Na+/Pi cotransporter; sodium-phosphate transport protein 2C; Na(+)-dependent ph;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
MYC

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SLC34A3-673H	Recombinant Human SLC34A3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	SLC34A3-15387M	Recombinant Mouse SLC34A3 Protein	Mammalian Cell	His	Inquiry
Mouse	SLC34A3-8329M-B	Recombinant Mouse SLC34A3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	SLC34A3-8329M	Recombinant Mouse SLC34A3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	Slc34a3-1027M	Recombinant Mouse Slc34a3 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Rat	SLC34A3-5512R	Recombinant Rat SLC34A3 Protein	Mammalian Cell	His	Inquiry
Rat	SLC34A3-5171R	Recombinant Rat SLC34A3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	SLC34A3-5171R-B	Recombinant Rat SLC34A3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC34A3 involved in several pathways and played different roles in them. We selected most pathways SLC34A3 participated on our site, such as SLC-mediated transmembrane transport, Sodium-coupled phosphate cotransporters, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC34A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SLC-mediated transmembrane transport	SLC28A1;SLC9A9;SLC43A2A;RHCGL1;SLC15A4;SLC44A5B;SLCO2A1;SLC9A3.1;SLC6A6
Sodium-coupled phosphate cotransporters	SLC20A2;SLC20A1A;SLC20A1B;SLC34A3;SLC34A2A;SLC20A1
Transmembrane transport of small molecules	ATP8B1;CTNS;SLC24A6;SLC9A6A;FKBP1B;ABCA8;SLC22A15;SLC39A5;SLC26A7
Transport of inorganic cations/anions and amino acids/oligopeptides	SLC26A3.2;SLC15A2;SLC36A2;SLC12A4;SLC9A5;SLC7A11;SLC20A1;SLC34A2A;SLC6A20A
Type II Na+/Pi cotransporters	SLC34A2A;SLC34A3

SLC34A3 has several biochemical functions, for example, sodium-dependent phosphate transmembrane transporter activity, sodium:phosphate symporter activity, symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC34A3 itself. We selected most functions SLC34A3 had, and list some proteins which have the same functions with SLC34A3. You can find most of the proteins on our site.

Function	Related Protein
sodium-dependent phosphate transmembrane transporter activity	SLC17A4;SLC17A1;SLC17A2;SLC34A2A;SLC17A7;SLC34A2;SLC34A3;SLC17A7A;SLC17A3
sodium:phosphate symporter activity	SLC20A1;SLC20A2;SLC17A3;SLC34A3;SLC17A4;SLC17A2;SLC34A2;SLC17A1
symporter activity	SLC17A6A;SLC6A11A;SLC36A4;SLC12A3;SLC1A7A;SLC38A4;SLC38A1;SLC6A20A;SLC23A2

SLC34A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC34A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC34A3.