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SLC35D2

  • Official Full Name

    solute carrier family 35, member D2

  • Overview

    Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for;glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of;nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters,;such as SLC35D2 (Suda et al., 2004 (PubMed 15082721)).
  • Synonyms

    SLC35D2; solute carrier family 35, member D2; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; SQV7L; UGTrel8; Fringe connection; HFRC 1; Hfrc; HFRC1; MGC117215; MGC142139; Nucleotide sugar transporter UGTrel8; Solute carrier family 35 member D2; SQV 7L; UDP N acetylglucosamine transporter; UGTrel 8; SQV7-like protein; OTTHUMP00000021719; UDP-N-acetylglucosamine transporter; homolog of Fringe connection protein 1; UDP-galactose transporter-related protein 8;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC35D2-667H Recombinant Human SLC35D2 Protein, GST-tagged Wheat Germ GST 1-249 aa
Human SLC35D2-6813HF Recombinant Full Length Human SLC35D2 Protein, GST-tagged In Vitro Cell Free System GST 249 amino acids
Mouse SLC35D2-15400M Recombinant Mouse SLC35D2 Protein Mammalian Cell His
Mouse SLC35D2-8337M-B Recombinant Mouse SLC35D2 Protein Pre-coupled Magnetic Beads HEK293
Mouse SLC35D2-8337M Recombinant Mouse SLC35D2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLC35D2 involved in several pathways and played different roles in them. We selected most pathways SLC35D2 participated on our site, such as Glycosaminoglycan metabolism, HS-GAG biosynthesis, Heparan sulfate/heparin (HS-GAG) metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC35D2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosaminoglycan metabolismB4GALT7;GPC5A;PRELP;ST3GAL3A;BGNB;UST;CHST9;KERA;OGN
HS-GAG biosynthesisGPC1B;HS3ST6;MAPK1IP1L;GPC5A;HS3ST4;Gpc2;GPC1A;SLC35D2
Heparan sulfate/heparin (HS-GAG) metabolismHS3ST4;SLC35D2;MAPK1IP1L;GLB1L;CSPG5B;GPC1A;Gpc2;B3GAT2;GPC1B
Keratan sulfate biosynthesisB3GNT1;OMD;PRELP;B3GNT3;ST3GAL3A;FMODA;B3GNT2;KERA;B3GNT2A
Keratan sulfate/keratin metabolismB3GNT1;OMD;B3GNT2A;FMODA;SLC35D2;ST3GAL3A;B3GNT2;GLB1L;B3GNT3
MetabolismADSL;ACSF3;DECR1;CYB5A;ABCA1;MED21;SPTLC1;SCO1;NAT2
Metabolism of carbohydratesHAS3;AGL;PYGMB;B3GNT2;HPSE;TREH;PFKLB;OXSR1;B3GNT3
SLC-mediated transmembrane transportSLC13A4;SLC20A2;SLC6A2;SLC28A3;SLC6A19B;SLC34A2A;SLC6A7;SLC6A1A;CP

SLC35D2 has several biochemical functions, for example, antiporter activity, pyrimidine nucleotide-sugar transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC35D2 itself. We selected most functions SLC35D2 had, and list some proteins which have the same functions with SLC35D2. You can find most of the proteins on our site.

Function Related Protein
antiporter activitySLC35E3;CLCN4;SLC7A6;SLC9A6B;SLC25A16;SLC7A1;SLC35D1B;SLC7A10;SLC7A7
pyrimidine nucleotide-sugar transmembrane transporter activitySLC35D1A;SLC35D2;SLC35D1B

SLC35D2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC35D2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC35D2.

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