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SLC37A4

Official Full Name

solute carrier family 37 (glucose-6-phosphate transporter), member 4
Overview

This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.
Synonyms

SLC37A4; solute carrier family 37 (glucose-6-phosphate transporter), member 4; G6PT1, G6PT2, G6PT3, glucose 6 phosphatase, transport (glucose 6 phosphate) protein 1; glucose-6-phosphate translocase; GSD1b; GSD1c; GSD1d; G6PT2; MGC15729; PRO0685; TRG19; G6PT1; G6PT1_HUMAN; G6PT3; Glucose-5-phosphate transporter; Glucose-6-phosphatase, transport (glucose) protein 3; Glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1; Glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2; Glucose-6-phosphate transporter 1; Microsomal glucose-6-phosphate transporter; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque

Source

Baculovirus-Insect cells
E.coli
HEK293
Insect Cell
Mammalian Cell
Wheat Germ
Yeast

Tag

8His
MBP,Flag
C
His
GST
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC37A4-31417TH	Recombinant Human SLC37A4	Wheat Germ	N/A	49 amino acids	Inquiry
Human	SLC37A4-2758H	Recombinant Human SLC37A4, GST-tagged	E.coli	GST	1-93aa	$319 / 25ug
Human	SLC37A4-1726HCL	Recombinant Human SLC37A4 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SLC37A4-0416H	Recombinant Human SLC37A4 Protein (Met1-Cys176), C-His-tagged	Baculovirus-Insect cells	C-His	Met1-Cys176	Inquiry
Human	SLC37A4-5789H	Recombinant Human SLC37A4 Protein (Met1-Cys176), C-His tagged	Yeast	C-His	Met1-Cys176	Inquiry
Human	SLC37A4-0569H	Recombinant Human SLC37A4 Protein (A2-E429), 8×His-MBP, Flag tagged	Insect Cell	8His-MBP,Flag	A2-E429	Inquiry
Rhesus Macaque	SLC37A4-4282R	Recombinant Rhesus monkey SLC37A4 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SLC37A4-4098R	Recombinant Rhesus Macaque SLC37A4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	SLC37A4-4098R-B	Recombinant Rhesus Macaque SLC37A4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC37A4 Related Articles

SLC37A4 involved in several pathways and played different roles in them. We selected most pathways SLC37A4 participated on our site, such as Carbohydrate digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC37A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Carbohydrate digestion and absorption	ATP1A3;PRKCB;PLCB2;GNAT3;AMY2A;SLC2A2;FXYD2;SLC37A4;ATP1B1

SLC37A4 has several biochemical functions, for example, glucose-6-phosphate transmembrane transporter activity, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC37A4 itself. We selected most functions SLC37A4 had, and list some proteins which have the same functions with SLC37A4. You can find most of the proteins on our site.

Function	Related Protein
glucose-6-phosphate transmembrane transporter activity	SLC37A4;SLC37A4B;SLC37A4A
transporter activity	SLC5A6A;MIPA;PTGDSA;TMEM184B;FABP1A;SLC22A13;CPNE1;TTPAL;AP1S2

SLC37A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC37A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC37A4.

Franca, MR; Mesquita, FS; et al. Modulation of periovulatory endocrine profiles in beef cows: consequences for endometrial glucose transporters and uterine fluid glucose levels. DOMESTIC ANIMAL ENDOCRINOLOGY 50:83-90(2015).

Melis, D; Della Casa, R; et al. Involvement of endocrine system in a patient affected by Glycogen storage disease 1b: speculation on the role of autoimmunity. ITALIAN JOURNAL OF PEDIATRICS 40:-(2014).