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SLC3A2

  • Official Full Name

    solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

  • Overview

    This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
  • Synonyms

    4F2; CD98; MDU1; 4F2HC; 4T2HC; NACAE; CD98HC; SLC3A2; 4F2 cell-surface antigen heavy chain; heavy chain; CD98 heavy chain; OTTHUMP00000082735; OTTHUMP00000236708; OTTHUMP00000236709; OTTHUMP00000236712; OTTHUMP00000238367; 4F2 heavy chain antigen Monoclonal 44D7; lymphocyte activation antigen 4F2 large subunit; antigen defined by Monoclonal 4F2, heavy chain; antigen identified by Monoclonal antibodies 4F2, TRA1.10, TROP4, and T43;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Baculovirus-Infected Sf9 Cells
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • hFc
  • His
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC3A2-587H Active Recombinant Human SLC3A2, Fc-tagged, Biotinylated Human Cell Fc
Human SLC3A2-588H Active Recombinant Human SLC3A2, Fc-tagged Human Cell Fc
Human SLC3A2-3960H Recombinant Human SLC3A2 protein, His-tagged HEK293 His Arg206-Ala630
Human SLC3A2-26956TH Recombinant Human SLC3A2 Wheat Germ N/A 110 amino acids
Human SLC3A2-2768H Recombinant Human SLC3A2 protein, His-tagged E.coli His 269-630 aa
Human SLC3A2-2015HCL Recombinant Human SLC3A2 cell lysate Human Cell N/A
Human SLC3A2-2568H Active Recombinant Human SLC3A2 protein Baculovirus-Infected Sf9 Cells N/A Arg206-Ala630
Human SLC3A2-1037H Recombinant Human SLC3A2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SLC3A2-1057H Recombinant Human SLC3A2 protein(Arg206-Ala630), His-tagged, Biotinylated HEK293 N-His Arg206-Ala630
Human SLC3A2-229H Recombinant Human SLC3A2 Protein, His-tagged Insect Cell His 206-630aa
Human SLC3A2-2592H Recombinant Human SLC3A2 protein(271-390 aa), C-His-tagged E. coli C-His 271-390 aa
Human SLC3A2-175H Recombinant Human SLC3A2 Protein, His-tagged HEK293 His 630
Human SLC3A2-2328H Recombinant Human SLC3A2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SLC3A2-1425H Recombinant Human SLC3A2 Protein (Leu213-Asp349), N-His tagged E.coli N-His Leu213-Asp349
Human SLC3A2-5106H Recombinant Human SLC3A2 Protein (Arg206-Ala630), N-His tagged Mammalian cells N-His Arg206-Ala630
Human SLC3A2-5107H Recombinant Human SLC3A2 Protein (Arg206-Ala630), C-His tagged Mammalian cells C-His Arg206-Ala630
Human SLC3A2-2593H Recombinant Human SLC3A2 protein(271-370 aa), C-hFc & C-His-tagged HEK293 C-hFc & C-His 271-370 aa
Mouse Slc3a2-1196M Recombinant Mouse Slc3a2 protein, His & GST-tagged E.coli His/GST Ile285~Gln522 (Accession # P10852)
Mouse Slc3a2-7031M Recombinant Mouse Slc3a2 protein(Ala139-Ala565), His-tagged HEK293 N-His Ala139-Ala565
Mouse SLC3A2-1772MCL Recombinant Mouse SLC3A2 cell lysate Human Cell N/A
Mouse Slc3a2-5933M Recombinant Mouse Slc3a2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Slc3a2-8781R Recombinant Rat Slc3a2, His tagged Human Cell GST
Rat SLC3A2-5538R Recombinant Rat SLC3A2 protein, His-tagged HEK293 His Ala100-Ala527
Rat Slc3a2-1197R Recombinant Rat Slc3a2 protein, His & GST-tagged E.coli His/GST Ile282~Phe523 (Accession # Q794F9)
Rat SLC3A2-1199RCL Recombinant Rat SLC3A2 cell lysate Human Cell N/A
Rat SLC3A2-949R Recombinant Rat SLC3A2 protein(Ala100-Ala527), hFc-tagged HEK293 N-hFc Ala100-Ala527
Rat SLC3A2-5197R Recombinant Rat SLC3A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC3A2-5197R-B Recombinant Rat SLC3A2 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL17565HF Recombinant Full Length Human 4F2 Cell-Surface Antigen Heavy Chain(Slc3A2) Protein, His-Tagged E.coli expression system His Full Length (1-630)
Mus musculus (Mouse) RFL45MF Recombinant Full Length Mouse 4F2 Cell-Surface Antigen Heavy Chain(Slc3A2) Protein, His-Tagged E.coli expression system His Full Length (1-526)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC3A2 Related Articles

SLC3A2 involved in several pathways and played different roles in them. We selected most pathways SLC3A2 participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC3A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein digestion and absorptionSLC15A1;COL6A5;PRSS2;COL18A1;MEP1A;KCNK5;CELA2A;SLC3A1;COL6A4

SLC3A2 has several biochemical functions, for example, calcium:sodium antiporter activity, catalytic activity, cation binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC3A2 itself. We selected most functions SLC3A2 had, and list some proteins which have the same functions with SLC3A2. You can find most of the proteins on our site.

Function Related Protein
calcium:sodium antiporter activitySLC8A2A;SLC8A4A;SLC8A2B;SLC8A1;SLC8A1A;SLC24A6;SLC8A4B;SLC8A2;SLC3A2
catalytic activityFHIT;CAPN3;LDHBA;PNP5B;PPM1BB;ASAH1;PKMA;PNP4A;SYN2A
cation bindingPPM1LA;PPM1E;Amy1;PPM1BB;SLC3A2;GBE1;SLC3A2B;PPM1NB;PPM1DB
double-stranded RNA bindingAPTX;ZFP346;MBNL1;ILF2;IFIH1;ZNF346;OAS1A;STRBP;TARBP2
neutral amino acid transmembrane transporter activitySLC43A1B;SLC15A1B;SLC43A2;SLC6A19B;SLC3A2;SLC43A2A;SLC43A1A;SLC43A2B;SLC7A10
poly(A) RNA bindingNCBP2;TXN;HSPD1;EXOSC10;HNRNPM;RPL22;TDRD3;ZRANB2;MAK16
protein bindingMTUS2;PSPC1;GEM;STXBP1;COMMD3;2610109H07Rik;SMPDL3A;MED8;NKX2-5

SLC3A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC3A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC3A2.

EGFR; PTP4A3; ARF6; TSC22D1; PHB2; BRF2; NEK6; GSTK1; PHLDA3; b3xyc5_sollc; 15-deoxy-delta(12,14; ere_dna; FN1; cona_canen

El-Mallawany, NK; Day, N; et al. Differential proteomic analysis of endemic and sporadic Epstein-Barr virus-positive and negative Burkitt lymphoma. EUROPEAN JOURNAL OF CANCER 51:92-100(2015).
Estrach, S; Lee, SA; et al. CD98hc (SLC3A2) Loss Protects Against Ras-Driven Tumorigenesis by Modulating Integrin-Mediated Mechanotransduction. CANCER RESEARCH 74:6878-6889(2014).
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