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SLC6A15

Official Full Name

solute carrier family 6 (neutral amino acid transporter), member 15
Overview

This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The;encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with;major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this;gene.
Synonyms

SLC6A15; solute carrier family 6 (neutral amino acid transporter), member 15; solute carrier family 6 (neurotransmitter transporter), member 15; sodium-dependent neutral amino acid transporter B(0)AT2; FLJ10316; homolog of rat orphan transporter v7 3; hv7;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SLC6A15-1706HCL	Recombinant Human SLC6A15 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	SLC6A15-15496M	Recombinant Mouse SLC6A15 Protein	Mammalian Cell	His	Inquiry
Mouse	SLC6A15-8406M-B	Recombinant Mouse SLC6A15 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	SLC6A15-8406M	Recombinant Mouse SLC6A15 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	SLC6A15-5565R	Recombinant Rat SLC6A15 Protein	Mammalian Cell	His	Inquiry
Rat	SLC6A15-5224R	Recombinant Rat SLC6A15 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	SLC6A15-5224R-B	Recombinant Rat SLC6A15 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	SLC6A15-8069Z	Recombinant Zebrafish SLC6A15	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC6A15 involved in several pathways and played different roles in them. We selected most pathways SLC6A15 participated on our site, such as Amino acid transport across the plasma membrane, Na+/Cl- dependent neurotransmitter transporters, SLC-mediated transmembrane transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC6A15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Amino acid transport across the plasma membrane	SLC6A20A;SLC7A11;SLC43A2A;SLC43A2;SLC6A15;SLC43A1B;SLC1A4;SLC38A4;SLC38A3
Na+/Cl- dependent neurotransmitter transporters	SLC6A19B;SLC6A1B;SLC6A2;SLC6A12;SLC6A20A;SLC6A19A;SLC6A9;SLC6A6A;SLC6A1A
SLC-mediated transmembrane transport	SLC22A7;SLC30A6;SLC4A2B;SLC5A6B;SLC35A1;SLC2A8;SLC9A7;SLC13A5A;SLC24A4A
Transmembrane transport of small molecules	SLC22A7A;ATP13A1;SGK2;WNK1;ADD3B;SLC6A20B;SLC20A1B;SLC30A2;ABCF1
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	SLC2A15B;SLC22A6;SLC2A13;SLC39A2;SLC6A6;SLC5A4;SLC30A1A;SLC6A20;RHCGA
Transport of inorganic cations/anions and amino acids/oligopeptides	SLC4A2B;SLC12A3;SLC6A6;SLC43A1B;SLC1A7A;SLC43A2A;SLC6A20A;SLC12A4;SLC26A6L

SLC6A15 has several biochemical functions, for example, neurotransmitter transporter activity, neurotransmitter:sodium symporter activity, proline:sodium symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC6A15 itself. We selected most functions SLC6A15 had, and list some proteins which have the same functions with SLC6A15. You can find most of the proteins on our site.

Function	Related Protein
neurotransmitter transporter activity	SLC6A15;CPLX3;GABRQ;CPLX1
neurotransmitter:sodium symporter activity	SLC6A19A;SLC6A2;SLC6A7;SLC6A18;SLC6A16B;SLC6A4A;SLC6A11;SLC6A1B;SLC6A8
proline:sodium symporter activity

SLC6A15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC6A15 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC6A15.