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SLIT1

Official Full Name

slit homolog 1
Overview

Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene.
Synonyms

SLIT1; slit homolog 1 (Drosophila); SLIL1, slit (Drosophila) homolog 1; slit homolog 1 protein; MEGF4; Slit 1; SLIT3; multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains protein 4; SLIL1; SLIT-1; MGC164811;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

CHO
E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLIT1-524H	Active Recombinant Human SLIT1 Protein, His-tagged	CHO	His	Met1-Gln915	Inquiry
Human	SLIT1-19H	Active Recombinant Human Slit1, His-tagged	CHO	His		Inquiry
Human	SLIT1-7993H	Recombinant Human SLIT1 protein, His-tagged	E.coli	His	Ile345~Asn623 (Accession # O75093)	Inquiry
Human	SLIT1-7994H	Recombinant Human SLIT1 protein, His-tagged	E.coli	His	Asn647~Arg835 (Accession # O75093)	Inquiry
Human	SLIT1-330HL	Recombinant Human SLIT1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	Slit1-7995M	Recombinant Mouse Slit1 protein, His-tagged	E.coli	His	Leu3~Arg211 (Accession # Q80TR4)	Inquiry
Mouse	SLIT1-15562M	Recombinant Mouse SLIT1 Protein	Mammalian Cell	His		Inquiry
Mouse	SLIT1-8445M-B	Recombinant Mouse SLIT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SLIT1-8445M	Recombinant Mouse SLIT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SLIT1-5601R	Recombinant Rat SLIT1 Protein	Mammalian Cell	His		Inquiry
Rat	Slit1-7996R	Recombinant Rat Slit1 protein, His-tagged	E.coli	His	Leu3~Glu112 (Accession # O88279)	Inquiry
Rat	SLIT1-5260R	Recombinant Rat SLIT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SLIT1-5260R-B	Recombinant Rat SLIT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	SLIT1-4760C	Recombinant Chicken SLIT1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLIT1 Related Articles

SLIT1 involved in several pathways and played different roles in them. We selected most pathways SLIT1 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Axon guidance	DUSP10;KLB;PAQR3A;NFATC4;EPHB4B;KDR;NTNG1;RNF8;RHOD

SLIT1 has several biochemical functions, for example, Roundabout binding, calcium ion binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLIT1 itself. We selected most functions SLIT1 had, and list some proteins which have the same functions with SLIT1. You can find most of the proteins on our site.

Function	Related Protein
Roundabout binding	SLIT1A;SLIT2;TGFB1I1;UBE4A;SLIT3;GM4980;SLIT1;SLIT1B
calcium ion binding	CALM4;MFGE8A;CABP5A;PCDH21;EMR4;PCDH2AB2;BGLAP-RS1;PCDHGA1;PCDH2G29
heparin binding	THBS3;FMOD;APPB;FGFR4;ECM2;BSPH1;Itgam&Itgb2;APLP2;WISP1B

SLIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLIT1.

ATN1; q9wmx2-pro_0000037548

Kim, M; Fontelonga, T; et al. Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction. DEVELOPMENTAL BIOLOGY 399:68-79(2015).

Gangaraju, S; Sultan, K; et al. Cerebral endothelial expression of Robo1 affects brain infiltration of polymorphonuclear neutrophils during mouse stroke recovery. NEUROBIOLOGY OF DISEASE 54:24-31(2013).

Ghoshal, K; Motiwala, T; et al. HOxB13, a Target of DNMT3B䀤 Is Methylated at an Upstream CpG I3land, and ⁆ၵnctions as a Tumor ѓuppၲessor in Primary Colorectal Tumors. PLOSĠONE 4:-e10338(5).

Knoll, B; Schmidt, H; et al. On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion. DEVELOPMENT 130:5073-5082(2003).