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SMARCAD1

Official Full Name

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Overview

This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the;restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by;mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively;spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms

SMARCAD1; SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1; DKFZp762K2015; ETL1; KIAA1122; ATP dependent helicase 1; ATP-dependent helicase 1; hHEL1; SMRCD_HUMAN; OTTHUMP00000161594; OTTHUMP00000161595; OTTHUMP00000219301; OTTHUMP00000219302; HEL1; ADERM;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell

Tag

C
Myc
DDK
His
His (Fc)
Avi
MYC
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SMARCAD1-1670HCL	Recombinant Human SMARCAD1 293 Cell Lysate	HEK293	N/A	Inquiry
Human	SMARCAD1-01HFL	Recombinant Full Length Human SMARCAD1 Protein, C-Myc/DDK-tagged	HEK293T	C-Myc/DDK	Inquiry
Human	SMARCAD1-5273H	Recombinant Human SMARCAD1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	SMARCAD1-15599M	Recombinant Mouse SMARCAD1 Protein	Mammalian Cell	His	Inquiry
Mouse	SMARCAD1-8463M	Recombinant Mouse SMARCAD1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	Smarcad1-978M	Recombinant Mouse Smarcad1 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Mouse	SMARCAD1-8463M-B	Recombinant Mouse SMARCAD1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	SMARCAD1-2914Z	Recombinant Zebrafish SMARCAD1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

SMARCAD1 involved in several pathways and played different roles in them. We selected most pathways SMARCAD1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCAD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells	DLX5;BMPR1A;NODAL;NRAS;FZD5;WNT9A;ACVR2A;PIK3CG;FZD6

SMARCAD1 has several biochemical functions, for example, ATP binding, DNA binding, helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCAD1 itself. We selected most functions SMARCAD1 had, and list some proteins which have the same functions with SMARCAD1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	CSNK1D;ATP6V1B2;UPF1;RAF1;KIF6;ATP4A;MAP3K2;FARS2;BRAF
DNA binding	TTC4;FOXD1L;KCNA3;KLF14;THRAA;HOXA9B;ZNF225;BLM;VDR
helicase activity	MCM9;ERCC6L;DDX58;DHX32A;EIF4A1;HLTF;DDX3;DDX39AA;PL10
nucleic acid binding	REXO4;HNRPKL;ZBTB42;ENOX2;ZFP110;ZFP524;SSX2;ZFP287;BICC1
protein binding	FYN;STX12;PRDM5;DDC;KDM1A;SOCS1;KLHL38;MMP2;H3F3C

SMARCAD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCAD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCAD1.

MYC; EPHA2; SNW1; ESR2; CDC5L