Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SMARCB1

  • Official Full Name

    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

  • Overview

    The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; RDT; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; hSNF5; SNF5 homolog; BRG1-associated factor 47; integrase interactor 1 protein; malignant rhabdoid tumor suppressor; SWI/SNF-related matrix-associated protein; sucrose nonfermenting, yeast, homolog-like 1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SMARCB1-1647HCL Recombinant Human SMARCB1 cell lysate N/A
Human SMARCB1-1013H Recombinant Human SMARCB1 Protein (2-376 aa), His-SUMO-tagged E.coli His/SUMO 2-376 aa
Human SMARCB1-2740H Recombinant Human SMARCB1 Protein (2-376 aa), His-tagged Insect Cell His 2-376 aa
Human SMARCB1-1910H Recombinant Human SMARCB1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SMARCB1-3763H Recombinant Human SMARCB1 protein, GST-tagged E.coli GST 1-110 aa
Human SMARCB1-1660H Recombinant Human SMARCB1 Protein (2-376 aa), His-tagged Yeast His 2-376 aa
Human SMARCB1-4434H Recombinant Human SMARCB1 protein, His-tagged E.coli His 2-376aa
Human SMARCB1-6177H Recombinant Human SMARCB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Smarcb1-5960M Recombinant Mouse Smarcb1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque SMARCB1-4337R Recombinant Rhesus monkey SMARCB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SMARCB1-4153R-B Recombinant Rhesus Macaque SMARCB1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SMARCB1-4153R Recombinant Rhesus Macaque SMARCB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SMARCB1 Related Articles
  • SMARCB1 Related Research Area

SMARCB1 involved in several pathways and played different roles in them. We selected most pathways SMARCB1 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, RMTs methylate histone arginines, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesMBIP;GATAD2B;KDM7AB;KDM4A;PBRM1;PADI6;SMARCC1B;SMARCB1A;TADA2B
Chromatin organizationSUZ12A;CARM1;PBRM1;JHDM1D;PADI6;SMARCB1B;AEBP2;DR1;ACTL6A
RMTs methylate histone argininesSMARCB1B;ARID1A;PBRM1L;SMARCE1;SMARCB1;SMARCC1;SMARCA4;PRMT7;SMARCD3B
Regulation of retinoblastoma proteinGSC;AATF;BGLAP;CBX4;ELF1;ATF7;MYOD1;CKM;BRD2
TNF-alpha/NF-kB Signaling PathwayKTN1;PPP1R13L;COPS3;KIAA1967;RNF25;TIFA;MCC;NR2C2;PFDN2

SMARCB1 has several biochemical functions, for example, DNA binding, RNA polymerase I CORE element sequence-specific DNA binding, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCB1 itself. We selected most functions SMARCB1 had, and list some proteins which have the same functions with SMARCB1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingDBX1;PARP4;ZNF143B;SIM1B;PNX;PRIM2;ZNF789;ENG2A;RAD51B
RNA polymerase I CORE element sequence-specific DNA bindingEFCAB11;RRN3;SMARCB1;SMARCA4;TAF1B;TAF1C;PIH1D1;BAZ2A
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA bindingRBBP4;SMARCA4;GATAD2B;CHD4;SMARCC2;HDAC2;MBD3;SMARCE1;ACTB
contributes_to RNA polymerase II distal enhancer sequence-specific DNA bindingACTB;SMARCE1;SMARCA4;SMARCB1;ACTL6A;RBBP4;SMARCC1;CHD4;SMARCC2
Tat protein bindingNPM1;ACTB;SMARCA4;GABARAPL1;DLL1;MDFIC;SMARCB1;TRIM32
contributes_to nucleosomal DNA bindingACTB;CHD4;MBD3;SMARCE1;SMARCB1;MTA2;HDAC1;ACTL6A;RBBP4
p53 bindingDAXX;CREBBP;CDK5;NUAK1;ZNF385A;TRP53;USP10;HTT;BLM
protein bindingZC3HAV1;FUNDC1;ASAP3;SRPK1;BBS5;VIL1;TIMM10;LYL1;TCTEX1D1
transcription coactivator activityYY1;WNT3A;SAP130;PRMT2;TAF7;SOX10;CDK7;ING4;MED13

SMARCB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCB1.

SMARCA4

Yoshida, A; Asano, N; et al. Differential SALL4 immunoexpression in malignant rhabdoid tumours and epithelioid sarcomas. HISTOPATHOLOGY 66:252-261(2015).
Bartelheim, K; Sumerauer, D; et al. Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB). CANCER GENETICS 207:379-383(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SMARCB1 Products

Required fields are marked with *

My Review for All SMARCB1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends