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SMC4

  • Official Full Name

    structural maintenance of chromosomes 4

  • Overview

    Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi
  • Synonyms

    SMC4; structural maintenance of chromosomes 4; SMC4 (structural maintenance of chromosomes 4, yeast) like 1 , SMC4 structural maintenance of chromosomes 4 like 1 (yeast) , SMC4L1; structural maintenance of chromosomes protein 4; CAP C; hCAP C; SMC protein 4; XCAP-C homolog; chromosome-associated polypeptide C; SMC4 structural maintenance of chromosomes 4-like 1; CAPC; CAP-C; SMC-4; SMC4L1; hCAP-C;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SMC4-2811H Recombinant Human SMC4, GST-tagged E. coli GST
Human SMC4-1649HCL Recombinant Human SMC4 cell lysate N/A
Mouse SMC4-15612M Recombinant Mouse SMC4 Protein Mammalian Cell His
Mouse SMC4-8470M Recombinant Mouse SMC4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SMC4-8470M-B Recombinant Mouse SMC4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SMC4-4340R Recombinant Rhesus monkey SMC4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SMC4-4156R Recombinant Rhesus Macaque SMC4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SMC4-4156R-B Recombinant Rhesus Macaque SMC4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SMC4-9527Z Recombinant Zebrafish SMC4 Mammalian Cell His
Chicken SMC4-6087C Recombinant Chicken SMC4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SMC4 involved in several pathways and played different roles in them. We selected most pathways SMC4 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aurora B signalingSEPT1;SGOL1;RACGAP1;NCAPH;DES;EVI5;INCENP;NDC80;KIF20A
Cell CycleMCM10;NDEL1;ENSAB;CCND3;TP53BP1;HDAC1;GINS1;DCTN3;NUPL2
Cell Cycle, MitoticCDK6;CDKN2A;NDEL1;DYNC1H1;NEDD1;MCM8;SMC4;ACTR1A;CDCA5
Condensation of Prometaphase ChromosomesNCAPG;NCAPD2;SMC4;NCAPH;CSNK2B;CSNK2A2;SMC2;CSNK2A1
Condensation of Prophase ChromosomesH3F3D;SETB;MCPH1;NCAPD3;NCAPG2;SET;SMC4;H3F3B.1;NCAPH2
M PhaseCDCA8;CENPQ;SETB;CLIP1;KIF2B;RCC2;GORASP1;SGOL2;NUF2
Mitotic PrometaphaseNDEL1B;MIS12;NCAPD2;SGOL1;ZWINT;NDEL1A;NDEL1;SPDL1;CDCA8
Mitotic ProphaseSMC4;ENSA;MASTL;ARPP19A;CTDNEP1A;NEK6;MCPH1;ENSAA;VRK1

SMC4 has several biochemical functions, for example, ATP binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC4 itself. We selected most functions SMC4 had, and list some proteins which have the same functions with SMC4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingHSPA1B;WRNIP1;VARS;NLRP11;TTLL10;ATAD1;ATP5A1;JAK1;CKMT1A
protein bindingFAM162A;RSPH3;RAB41;COL18A1;ZBTB26;TRAPPC2;ZNF217;INTS12;ZNF785
protein heterodimerization activityBOKB;HIST2H2AA4;BAD;JAM3;HNF1B;ITGB1A;SEPHS1;TAF6L;TPD52L2

SMC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC4.

MYC; SMC2; NCAPH; MCC; CASP4; IKBKE; NCAPH2; SMYD2; PHLDA3; IKBKG; hmuT; tgt; metE; mtlR; hemH2

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