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SMN2

Official Full Name

sgp-130
Synonyms

sgp-130;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SMN2-1659HCL	Recombinant Human SMN2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SMN2-151H	Recombinant Human SMN2 Protein, DYKDDDDK-tagged	Human Cells	DYKDDDDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SMN2 Related Articles

SMN2 involved in several pathways and played different roles in them. We selected most pathways SMN2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA transport	XPO5;EIF1AXB;RANBP2;PABPC3;EIF4BB;EIF1B;RBM8A;EIF3E;NUP62L

SMN2 has several biochemical functions, for example, RNA binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMN2 itself. We selected most functions SMN2 had, and list some proteins which have the same functions with SMN2. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	THUMPD3;KHDRBS1A;TNRC6B;FAM103A1;SNRPE;RBMY1F;RBMS2;PES;PAPOLA
identical protein binding	HTT;REG3B;MAPK1IP1;PAFAH1B3;ALDOB;CBLL1;DHX8;COL1A1;SMAD6
protein binding	NDUFS7;NECAB3;FABP2;TJP2;KCTD15;RAD51B;C1orf51;RPLP2;RGS3

SMN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMN2.

GEMIN2

Mulcahy, PJ; Iremonger, K; et al. Gene Therapy: A Promising Approach to Treating Spinal Muscular Atrophy. HUMAN GENE THERAPY 25:575-586(2014).

Mattis, VB; Butchbach, MER; et al. Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: Applicability to preclinical therapy development for spinal muscular atrophy. JOURNAL OF NEUROSCIENCE METHODS 175:36-43(2008).