SMNDC1
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Official Full Name
survival motor neuron domain containing 1
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Overview
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. -
Synonyms
SMNDC1; survival motor neuron domain containing 1; survival of motor neuron-related-splicing factor 30; SMNR; SPF30; splicing factor 30; survival of motor neuron related; SMN-related protein; 30 kDa splicing factor SMNrp; survival motor neuron domain-cont;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Fc
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
SMNDC1 involved in several pathways and played different roles in them. We selected most pathways SMNDC1 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMNDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | RP9;HNRNPA1B;THOC4;HSC70;SNRPD2;SNRPD3;PRPF6;SF3B5;SRSF6A |
SMNDC1 has several biochemical functions, for example, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMNDC1 itself. We selected most functions SMNDC1 had, and list some proteins which have the same functions with SMNDC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | RRP8;MTIF2;RPP25;PPP1CC;LSM4;ZFR;FTSJ3;EIF4A2;ALDH18A1 |
| protein binding | ARHGEF38;NR4A2;TDP2;FSTL3;TP73;CDC20B;LBH;CD74;IL7 |
SMNDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMNDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMNDC1.
PRPF3; 33457355; SF3B1; SNRPA1; SNRPB; FDFT1; RPL3; MAPKAPK2; EWSR1; SF3A3; IFT88; SF3B2; RRP1B; KPNB1; SF3B3; SF3B4; SF3A2
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