SNAP29
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Official Full Name
synaptosomal-associated protein, 29kDa
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Overview
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. -
Synonyms
SNAP29; synaptosomal-associated protein, 29kDa; synaptosomal associated protein, 29kD; synaptosomal-associated protein 29; CEDNIK; SNAP 29; soluble 29 kDa NSF attachment protein; FLJ21051; SNAP-29; SNP29_HUMAN; Synaptosomal associated protein 29; Synaptosomal associated protein 29kDa; Vesicle membrane fusion protein SNAP 29; Vesicle membrane fusion protein SNAP29; Vesicle-membrane fusion protein SNAP-29; OTTHUMP00000198464; OTTHUMP00000198533;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- SNAP29 Related Research Area
SNAP29 involved in several pathways and played different roles in them. We selected most pathways SNAP29 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNAP29 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SNARE interactions in vesicular transport | VAMP3;STX19;VTI1A;VAMP8;STX8;STX2;STX18;SYBL1;STX1A |
SNAP29 has several biochemical functions, for example, SNAP receptor activity, protein binding, syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNAP29 itself. We selected most functions SNAP29 had, and list some proteins which have the same functions with SNAP29. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SNAP receptor activity | SEC22A;BNIP1;SEC22C;VAMP8;VAMP7;VTI1A;STX18;VAMP2;STX16 |
| protein binding | MYBPC1;RPS3;FOXR1;SEC61B;HERPUD1;SHPRH;AGXT2L2;CEP57L1;CMKLR1 |
| syntaxin binding | SYT4;CPLX3A;STX6;SYT11B;STXBP5A;CPLX3;CPLX4C;TMED9;CPLX2 |
SNAP29 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNAP29 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNAP29.
STX12; VAMP4; VAMP5; VAMP1; VAMP2; FAM9B; ATF4
- Q&As
- Reviews
Q&As (5)
Ask a questionDiagnostic methods include genetic testing to identify mutations in the SNAP29 gene, as well as clinical examinations and imaging studies to assess the manifestation of associated symptoms.
SNAP29 is involved in the assembly of SNARE complexes, which mediate the fusion of transport vesicles with their target membranes, facilitating the trafficking of proteins and lipids within cells.
Given its role in membrane fusion and intracellular trafficking, SNAP29 is being explored as a potential therapeutic target for other neurodevelopmental disorders characterized by similar cellular defects.
Yes, research is underway to explore the potential of targeting SNAP29 for the development of new therapeutic interventions for CEDNIK syndrome and related disorders.
SNAP29 interacts with other SNARE proteins, as well as regulatory proteins and lipids, to orchestrate the fusion of vesicles with target membranes in a regulated and coordinated manner.
Customer Reviews (3)
Write a reviewit has demonstrated remarkable effectiveness in ELISA experiments, showcasing its reliability and accuracy in detecting and quantifying specific targets.
The reliable performance of the SNAP29 protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.
the SNAP29 protein has proven to be an invaluable asset in protein electron microscopy structure analysis.
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