SNRNP70
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Official Full Name
small nuclear ribonucleoprotein 70kDa (U1)
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Overview
snRNP70 also known as U1 small nuclear ribonucleoprotein 70 kDa is a protein that in humans is encoded by the SNRNP70 gene. snRNP70 is a small nuclear ribonucleoprotein that associates with U1 spliceosomal RNA, forming part of the spliceosome. -
Synonyms
SNRNP70; small nuclear ribonucleoprotein 70kDa (U1); RNPU1Z, RPU1, small nuclear ribonucleoprotein 70kDa (RNP antigen) , SNRP70; U1 small nuclear ribonucleoprotein 70 kDa; Snp1; U1 70K; U1 snRNP 70 kDa; RPU1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
SNRNP70 involved in several pathways and played different roles in them. We selected most pathways SNRNP70 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRNP70 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Spliceosome | SNRPA1;SNRPD1;SR140;SRSF1;SNRPD3L;SRSF6A;USP39;HNRNPA1B;DDX42 |
SNRNP70 has several biochemical functions, for example, RNA binding, U1 snRNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRNP70 itself. We selected most functions SNRNP70 had, and list some proteins which have the same functions with SNRNP70. You can find most of the proteins on our site.
Function | Related Protein |
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RNA binding | SKIV2L;RPS25;PABPC5;EIF3B;SNRPE;RBM48;C14orf166;CELF2;DDX43 |
U1 snRNA binding | SNRPA;PRPF8;ISG20;SNRNP70 |
mRNA binding | NOVA1;LUC7L3;FXR1;LUC7L2;LUC7L;EIF4A1;RBFOX2;PARK7;CSTF2 |
nucleotide binding | ARL8;RBMS2B;ATP2B1A;ENOX1;SNRKB;ZRSR2;RAB1BA;GSK3AB;GNA12A |
poly(A) RNA binding | Cstb;NGDN;FNDC3B;CLK3;NUFIP2;TRIM25;MBNL3;DDX52;GFM1 |
protein binding | MTPAP;PFKFB2;CENPL;ARHGAP26;STK10;KIF1B;USP47;TCOF1;PYGM |
SNRNP70 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRNP70 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRNP70.
SRPK2; RNPS1; VCAM1; CLK2; SRPK1; WBP4; MYC; SFPQ; GSK3B; SF3A2; PRMT5; SMAD9; PRPF40A
- Q&As
- Reviews
Q&As (5)
Ask a questionAutoantibodies against SNRNP70 are frequently found in individuals with autoimmune diseases, serving as a diagnostic marker for conditions like SLE.
Common methods include immunoprecipitation, enzyme-linked immunosorbent assay (ELISA), and Western blotting.
Monitoring anti-SNRNP70 antibody levels during treatment may offer insights into the effectiveness of therapeutic interventions in autoimmune diseases.
Understanding the role of SNRNP70 in autoimmune diseases could lead to the development of targeted therapies aimed at modulating its activity.
Yes, anti-SNRNP70 antibodies are also associated with other autoimmune diseases such as mixed connective tissue disease (MCTD) and rheumatoid arthritis.
Customer Reviews (3)
Write a reviewThis may include providing detailed protocols, troubleshooting advice, and suggestions for experimental design.
The manufacturer can provide researchers with high-quality ARMC6 protein, ensuring it is properly purified, characterized, and quality-controlled.
This collaboration may extend beyond the purchase of the SNRNP70 protein, potentially leading to additional support, joint research projects, or access to expertise in the field.
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