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SNRNP70

  • Official Full Name

    small nuclear ribonucleoprotein 70kDa (U1)

  • Overview

    snRNP70 also known as U1 small nuclear ribonucleoprotein 70 kDa is a protein that in humans is encoded by the SNRNP70 gene. snRNP70 is a small nuclear ribonucleoprotein that associates with U1 spliceosomal RNA, forming part of the spliceosome.
  • Synonyms

    SNRNP70; small nuclear ribonucleoprotein 70kDa (U1); RNPU1Z, RPU1, small nuclear ribonucleoprotein 70kDa (RNP antigen) , SNRP70; U1 small nuclear ribonucleoprotein 70 kDa; Snp1; U1 70K; U1 snRNP 70 kDa; RPU1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNRNP70-227H Recombinant Human SNRNP70 protein E.coli N/A
Human SNRNP70-227 Recombinant Human SNRNP70, His-tagged E.coli His
Human SNRNP70-1620HCL Recombinant Human SNRNP70 293 Cell Lysate HEK293 N/A
Human SNRNP70-1036H Recombinant Human SNRNP70 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SNRNP70-2059H Recombinant Human SNRNP70 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SNRNP70-2711H Recombinant Human SNRNP70 Protein, His-tagged E.coli N-His Met1-Glu437
Human SNRNP70-1189HFL Recombinant Full Length Human SNRNP70 Protein, C-Flag-tagged Mammalian cells Flag
Human SNRNP70-2059H-B Recombinant Human SNRNP70 Protein Pre-coupled Magnetic Beads HEK293
Mouse Snrnp70-6003M Recombinant Mouse Snrnp70 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque SNRNP70-4374R Recombinant Rhesus monkey SNRNP70 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SNRNP70-4190R Recombinant Rhesus Macaque SNRNP70 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SNRNP70-4190R-B Recombinant Rhesus Macaque SNRNP70 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SNRNP70-1162Z Recombinant Zebrafish SNRNP70 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SNRNP70 involved in several pathways and played different roles in them. We selected most pathways SNRNP70 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRNP70 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SpliceosomeSNRPA1;SNRPD1;SR140;SRSF1;SNRPD3L;SRSF6A;USP39;HNRNPA1B;DDX42

SNRNP70 has several biochemical functions, for example, RNA binding, U1 snRNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRNP70 itself. We selected most functions SNRNP70 had, and list some proteins which have the same functions with SNRNP70. You can find most of the proteins on our site.

Function Related Protein
RNA bindingSKIV2L;RPS25;PABPC5;EIF3B;SNRPE;RBM48;C14orf166;CELF2;DDX43
U1 snRNA bindingSNRPA;PRPF8;ISG20;SNRNP70
mRNA bindingNOVA1;LUC7L3;FXR1;LUC7L2;LUC7L;EIF4A1;RBFOX2;PARK7;CSTF2
nucleotide bindingARL8;RBMS2B;ATP2B1A;ENOX1;SNRKB;ZRSR2;RAB1BA;GSK3AB;GNA12A
poly(A) RNA bindingCstb;NGDN;FNDC3B;CLK3;NUFIP2;TRIM25;MBNL3;DDX52;GFM1
protein bindingMTPAP;PFKFB2;CENPL;ARHGAP26;STK10;KIF1B;USP47;TCOF1;PYGM

SNRNP70 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRNP70 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRNP70.

SRPK2; RNPS1; VCAM1; CLK2; SRPK1; WBP4; MYC; SFPQ; GSK3B; SF3A2; PRMT5; SMAD9; PRPF40A

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is SNRNP70 linked to autoimmune diseases? 05/05/2018

Autoantibodies against SNRNP70 are frequently found in individuals with autoimmune diseases, serving as a diagnostic marker for conditions like SLE.

Are there specific techniques used to detect anti-SNRNP70 antibodies? 08/23/2017

Common methods include immunoprecipitation, enzyme-linked immunosorbent assay (ELISA), and Western blotting.

Can changes in SNRNP70 levels be used to monitor treatment response in autoimmune diseases? 07/10/2017

Monitoring anti-SNRNP70 antibody levels during treatment may offer insights into the effectiveness of therapeutic interventions in autoimmune diseases.

How might SNRNP70 be a potential therapeutic target? 03/19/2017

Understanding the role of SNRNP70 in autoimmune diseases could lead to the development of targeted therapies aimed at modulating its activity.

Can anti-SNRNP70 antibodies be found in diseases other than SLE? 09/24/2016

Yes, anti-SNRNP70 antibodies are also associated with other autoimmune diseases such as mixed connective tissue disease (MCTD) and rheumatoid arthritis.

Customer Reviews (3)

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Reviews
02/06/2022

    This may include providing detailed protocols, troubleshooting advice, and suggestions for experimental design.

    04/27/2019

      The manufacturer can provide researchers with high-quality ARMC6 protein, ensuring it is properly purified, characterized, and quality-controlled.

      12/17/2018

        This collaboration may extend beyond the purchase of the SNRNP70 protein, potentially leading to additional support, joint research projects, or access to expertise in the field.

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