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SNRPC

  • Official Full Name

    small nuclear ribonucleoprotein polypeptide C

  • Overview

    This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.
  • Synonyms

    SNRPC; small nuclear ribonucleoprotein polypeptide C; U1 small nuclear ribonucleoprotein C; U1 C; Yhc1; U1 snRNP C; U1 snRNP protein C; U1 small nuclear RNP specific C; U1C; FLJ20302;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Macaca mulatta (Rhesus macaque)
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNRPC-1323H Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide C, His-tagged E.coli His
Human SNRPC-30605TH Recombinant Human SNRPC, His-tagged E.coli His 159 amino acids
Human SNRPC-30583TH Recombinant Human SNRPC Wheat Germ N/A 159 amino acids
Human SNRPC-616HCL Recombinant Human SNRPC lysate HEK293 N/A
Human SNRPC-486HF Recombinant Full Length Human SNRPC Protein In Vitro Cell Free System 159 amino acids
Human SNRPC-1005HFL Recombinant Full Length Human SNRPC Protein, C-Flag-tagged Mammalian cells Flag
Human SNRPC-2253H Recombinant Human SNRPC Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SNRPC-2062H-B Recombinant Human SNRPC Protein Pre-coupled Magnetic Beads HEK293
Human SNRPC-2822H Recombinant Human SNRPC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SNRPC-6328H Recombinant Human SNRPC Protein E.coli Tag Free
Human SNRPC-2062H Recombinant Human SNRPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SNRPC-6329H Recombinant Human SNRPC Protein (Met1-Arg159), N-His tagged E.coli N-His Met1-Arg159
Mouse Snrpc-6006M Recombinant Mouse Snrpc Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SNRPC-5648R Recombinant Rat SNRPC Protein Mammalian Cell His
Rat SNRPC-5307R Recombinant Rat SNRPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SNRPC-5307R-B Recombinant Rat SNRPC Protein Pre-coupled Magnetic Beads HEK293
Macaca mulatta (Rhesus macaque) SNRPC-5785M Recombinant Rhesus macaque SNRPC Protein (Met1-Arg159), N-His tagged E.coli N-His Met1-Arg159
Zebrafish SNRPC-9525Z Recombinant Zebrafish SNRPC Mammalian Cell His
Chicken SNRPC-5534C Recombinant Chicken SNRPC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SNRPC Related Articles

SNRPC involved in several pathways and played different roles in them. We selected most pathways SNRPC participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRPC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SpliceosomeLSM6;SRSF10;SRSF2A;ISY1-RAB43;HNRNPU;RBM8A;HNRNPA1;SFRS3B;WBP11

SNRPC has several biochemical functions, for example, NOT U1 snRNA binding, mRNA binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRPC itself. We selected most functions SNRPC had, and list some proteins which have the same functions with SNRPC. You can find most of the proteins on our site.

Function Related Protein
NOT U1 snRNA binding
mRNA bindingRBM8A;RBFOX3;SRRM4;CPSF6;EIF4A3;LUC7L3;DCP1B;C1QBP;PIWIL1
poly(A) RNA bindingSECISBP2;MRPL37;ABT1;DQX1;DSP;FUS;RBM5;PUM1;CRNKL1
pre-mRNA 5-splice site binding
protein bindingCCDC28B;RNF115;CIB4;DNM3;IRAK1BP1;MYO6;TRAPPC2L;Trf;PTPN3
protein homodimerization activityCAMK2A;BAX;ABCB10;PRDX4;ATPIF1;EPHX2;CDH13;CIDEA;FGFR2
single-stranded RNA bindingAGO3;IFIT5;TLR7;POLR2G;CBX4;ANXA1;STRBP;RBMX;IFIH1
zinc ion bindingPCGF2;RTN4IP1;PDLIM5B;GATA1A;ZCCHC10;BMI1;DDX41;LASP1;GM757

SNRPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRPC here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRPC.

RBM10; WDR83; SF3A2; RBFOX2; KHDRBS3; HNRNPF; HNRNPH2; ILF3; HNRNPD; GIGYF2; DDX42; AGGF1; WDR77; HNRNPUL1; RBM4; ssrna_ug

Kaneko, Y; Suwa, A; et al. Clinical associations with autoantibody reactivities to individual components of U1 small nuclear ribonucleoprotein. LUPUS 19:307-312(2010).
Jiang, C; Deshmukh, US; et al. Differential Responses to Smith D Autoantigen by Mice with HLA-DR and HLA-DQ Transgenes: Dominant Responses by HLA-DR3 Transgenic Mice with Diversification of Autoantibodies to Small Nuclear Ribonucleoprotein, Double-Stranded DNA, and Nuclear Antigens. JOURNAL OF IMMUNOLOGY 184:1085-1091(2010).
  • Q&As
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