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SNX12

  • Official Full Name

    sorting nexin 12

  • Overview

    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function.
  • Synonyms

    SNX12; sorting nexin 12; sorting nexin-12; 2610001F05Rik; AW045757; MGC118982; MGC118983; RGD1565585; RP23-356J7.1; SDP8; SNX 12; SNX12_HUMAN; OTTHUMP00000023487; OTTHUMP00000023488;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNX12-1601HCL Recombinant Human SNX12 293 Cell Lysate HEK293 N/A
Human SNX12-5648H Recombinant Human SNX12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Snx12-6022M Recombinant Mouse Snx12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque SNX12-4389R Recombinant Rhesus monkey SNX12 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SNX12-4205R Recombinant Rhesus Macaque SNX12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SNX12-4205R-B Recombinant Rhesus Macaque SNX12 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SNX12-7395Z Recombinant Zebrafish SNX12 Mammalian Cell His
Zebrafish SNX12-7396Z Recombinant Zebrafish SNX12 Mammalian Cell His
Zebrafish SNX12-7397Z Recombinant Zebrafish SNX12 Mammalian Cell His
Zebrafish SNX12-11345Z Recombinant Zebrafish SNX12 Mammalian Cell His
Chicken SNX12-3177C Recombinant Chicken SNX12 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SNX12 Related Articles

SNX12 involved in several pathways and played different roles in them. We selected most pathways SNX12 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisCLTCA;MHC1UXA2;HSC70;SMAD2;HSP70L;CLINT1A;PIP5K1BB;CHMP4A;ARFGEF1

SNX12 has several biochemical functions, for example, enzyme binding, phosphatidylinositol binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX12 itself. We selected most functions SNX12 had, and list some proteins which have the same functions with SNX12. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingAPOA1;HDAC2;MAPT;UGT1A6A;MARCH6;PARP4;KPNB1;TOP2B;SLC27A2
phosphatidylinositol bindingARHGAP33;SNX18B;SNX22;TULP3;RPS6KC1;SH3PXD2A;SNX10B;SNX12;RAG2
protein bindingRBMS1;MFF;CFL1;GLYR1;FAM156A;C1orf50;FOXP4;CCDC68;S100B

SNX12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX12.

ARL6IP1; ABL1; FYN; NCK1; GRB2; pi3p; CDC5L

Wang, X; Huang, T; et al. Dysregulation of protein trafficking in neurodegeneration. MOLECULAR NEURODEGENERATION 9:-(2014).
Angel, JM; Abel, EL; et al. Fine Mapping Reveals That Promotion Susceptibility Locus 1 (Psl1) Is a Compound Locus With Multiple Genes That Modify Susceptibility to Skin Tumor Development. G3-GENES GENOMES GENETICS 4:1071-1079(2014).
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