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SP110

Official Full Name

SP110 nuclear body protein
Overview

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Synonyms

SP110; SP110 nuclear body protein; IFI41, IFI75, interferon induced protein 41, 30kD; speckled 110 kDa; phosphoprotein 41; phosphoprotein 75; interferon-induced protein 41/75; transcriptional coactivator Sp110; interferon-indu;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SP110-2886H	Recombinant Human SP110, GST-tagged	E.coli	GST	N-term-350aa	$319 / 25ug
Human	SP110-31432TH	Recombinant Human SP110	Wheat Germ	N/A	110 amino acids	Inquiry
Human	SP110-203H	Recombinant Human SP110 Protein, GST-tagged	E.coli	GST	532-706	Inquiry
Human	SP110-1554HCL	Recombinant Human SP110 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	SP110-15791M	Recombinant Mouse SP110 Protein	Mammalian Cell	His		Inquiry
Mouse	SP110-8595M-B	Recombinant Mouse SP110 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SP110-8595M	Recombinant Mouse SP110 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SP110-5678R	Recombinant Rat SP110 Protein	Mammalian Cell	His		Inquiry
Rat	SP110-5337R	Recombinant Rat SP110 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SP110-5337R-B	Recombinant Rat SP110 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

SP110 involved in several pathways and played different roles in them. We selected most pathways SP110 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SP110 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SP110 has several biochemical functions, for example, DNA binding, chromatin binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SP110 itself. We selected most functions SP110 had, and list some proteins which have the same functions with SP110. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZFP488;FLI1;NKX2.9;MB21D2;HOXC8A;MBD1B;RAD51C;GPBP1L1;ZNF276
chromatin binding	SVEP1;ELK1;ATRX;HMGB4;SAFB;POLG;Trl;TPR;NUPR1
signal transducer activity	CCR1L1;GNAO1A;APLNRA;OLFR508;TAS2R140;GNGT2A;GHSRA;CXCR3.1;GPR132B
zinc ion binding	BRD1B;CAPNS2;PHF11;MTA2;CAR5A;RCHY1;SAMHD1;ENPEP;UBR4

SP110 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SP110 here. Most of them are supplied by our site. Hope this information will be useful for your research of SP110.

TTR; TK1; NDUFV2; ANXA7; CDKN1A; TSC22D1; SMN1; q81xc3_bacan; OSGEP