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SPA17

  • Official Full Name

    sperm autoantigenic protein 17

  • Overview

    This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
  • Synonyms

    SPA17; sperm autoantigenic protein 17; sperm surface protein Sp17; cancer/testis antigen 22; CT22; SP17; sperm protein 17; SP17-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SPA17-530H Recombinant Human sperm autoantigenic protein 17, His-tagged E.coli His
Human SPA17-31433TH Recombinant Human SPA17 N/A
Human SPA17-2890H Recombinant Human SPA17, GST-tagged E.coli GST 1-151aa
Human SPA17-1552HCL Recombinant Human SPA17 293 Cell Lysate HEK293 N/A
Human SPA17-5920H Recombinant Human SPA17 Protein (Met1-Gln143), N-His tagged E.coli N-His Met1-Gln143
Mouse Spa17-2001M Recombinant Mouse Spa17 protein, His & T7-tagged E.coli His/T7 Met1~Asn149 (Accession# Q62252)
Rat Spa17-2002R Recombinant Rat Spa17 protein, His & T7-tagged E.coli His/T7 Met1~Glu140 (Accession# Q9Z1K2)
Cynomolgus Monkey SPA17-960C Recombinant Cynomolgus SPA17 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SPA17-703C-B Recombinant Cynomolgus Monkey SPA17 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SPA17-703C Recombinant Cynomolgus Monkey SPA17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SPA17-4420R Recombinant Rhesus monkey SPA17 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SPA17-4236R Recombinant Rhesus Macaque SPA17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SPA17-4236R-B Recombinant Rhesus Macaque SPA17 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SPA17-4888Z Recombinant Zebrafish SPA17 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SPA17 involved in several pathways and played different roles in them. We selected most pathways SPA17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPA17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SPA17 has several biochemical functions, for example, calmodulin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPA17 itself. We selected most functions SPA17 had, and list some proteins which have the same functions with SPA17. You can find most of the proteins on our site.

Function Related Protein
calmodulin bindingMAPKAPK5;KCNH1;MYO3A;PATE4;SNTB2;GM101;C2orf62;CAMK2D1;ASPM
protein bindingCTDSP1;REG3A;NCOA2;RCN3;ZNF136;LUC7L;TLR3;TCF4;MRC1

SPA17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPA17 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPA17.

ROPN1; AKAP7; MYL6B

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