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SPAG16

Official Full Name

sperm associated antigen 16
Overview

Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and;surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the;nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 (PubMed 17699735)).
Synonyms

SPAG16; sperm associated antigen 16; sperm-associated antigen 16 protein; DKFZp666P1710; FLJ22724; PF20; WDR29; WD repeat domain 29; pf20 protein homolog; sperm-associated WD repeat protein; FLJ37717; MGC87036;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Cynomolgus Monkey
Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SPAG16-2892H	Recombinant Human SPAG16, His-tagged	E.coli	His	1-181aa	$319 / 25ug
Human	SPAG16-989H	Recombinant Human SPAG16 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	SPAG16-2510H	Recombinant Human SPAG16 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	SPAG16-1615H	Recombinant Human SPAG16 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	SPAG16-4631H	Recombinant Human SPAG16 protein, GST-tagged	E.coli	GST	1-183aa	Inquiry
Mouse	Spag16-6069M	Recombinant Mouse Spag16 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Cynomolgus Monkey	SPAG16-961C	Recombinant Cynomolgus SPAG16 Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	SPAG16-704C-B	Recombinant Cynomolgus Monkey SPAG16 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Cynomolgus Monkey	SPAG16-704C	Recombinant Cynomolgus Monkey SPAG16 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SPAG16 Related Articles

SPAG16 involved in several pathways and played different roles in them. We selected most pathways SPAG16 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPAG16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SPAG16 has several biochemical functions, for example, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPAG16 itself. We selected most functions SPAG16 had, and list some proteins which have the same functions with SPAG16. You can find most of the proteins on our site.

Function	Related Protein
protein kinase binding	CCNE2;ADCY6;KIF11;RPS6KA3;GATA4;IBTK;FER;TNIP2;EMP2

SPAG16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPAG16 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPAG16.

rpoH

Krabben, A; Huizinga, TWJ; et al. Biomarkers for Radiographic Progression in Rheumatoid Arthritis. CURRENT PHARMACEUTICAL DESIGN 21:147-169(2015).

de Bock, L; Somers, K; et al. Sperm-Associated Antigen 16 Is a Novel Target of the Humoral Autoimmune Response in Multiple Sclerosis. JOURNAL OF IMMUNOLOGY 193:2147-2156(2014).

Shi, Y; Zhang, L; et al. The mouse transcription factor-like 5 gene encodes a protein localized in the manchette and centriole of the elongating spermatid. ANDROLOGY 1:431-439(2013).

Somers, V; Govarts, C; et al. Autoantibody profiling in multiple sclerosis reveals novel antigenic candidates. JOURNAL OF IMMUNOLOGY 180:3957-3963(2008).