Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SPG21

  • Official Full Name

    spastic paraplegia 21 (autosomal recessive, Mast syndrome)

  • Overview

    The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
  • Synonyms

    SPG21; spastic paraplegia 21 (autosomal recessive, Mast syndrome); maspardin; ACP33; BM 019; GL010; MAST; Acid cluster protein 33; BM019; Spastic paraplegia 21 autosomal recessive Mast syndrome protein; OTTHUMP00000164130; spastic paraplegia 21 protein; BM-019;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SPG21-501H Recombinant Human Spastic Paraplegia 21, His-tagged E.coli His
Human SPG21-872H Recombinant Human SPG21 protein, GST-tagged Insect Cells GST Met1-Gln308
Human SPG21-30665TH Recombinant Human SPG21, His-tagged E.coli His
Human SPG21-726HCL Recombinant Human SPG21 cell lysate Insect Cell N/A
Human SPG21-2568H Recombinant Human SPG21 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SPG21-3706H Recombinant Human SPG21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse SPG21-914M Recombinant Mouse SPG21 Protein, GST & His-tagged Insect Cell GST/His
Mouse SPG21-454MCL Recombinant Mouse SPG21 cell lysate Insect Cell N/A
Mouse Spg21-6091M Recombinant Mouse Spg21 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SPG21-5703R Recombinant Rat SPG21 Protein Mammalian Cell His
Rat SPG21-5362R-B Recombinant Rat SPG21 Protein Pre-coupled Magnetic Beads HEK293
Rat SPG21-5362R Recombinant Rat SPG21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey SPG21-971C Recombinant Cynomolgus SPG21 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SPG21-714C-B Recombinant Cynomolgus Monkey SPG21 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SPG21-714C Recombinant Cynomolgus Monkey SPG21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SPG21-4433R Recombinant Rhesus monkey SPG21 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SPG21-4249R Recombinant Rhesus Macaque SPG21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SPG21-4249R-B Recombinant Rhesus Macaque SPG21 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SPG21-12570Z Recombinant Zebrafish SPG21 Mammalian Cell His
Chicken SPG21-4183C Recombinant Chicken SPG21 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SPG21 involved in several pathways and played different roles in them. We selected most pathways SPG21 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPG21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisCXCR4B;ARRB2A;RLN1;VPS26B;PSD3;KIF5AA;BF1;HLA-F;CYTH1A

SPG21 has several biochemical functions, for example, CD4 receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPG21 itself. We selected most functions SPG21 had, and list some proteins which have the same functions with SPG21. You can find most of the proteins on our site.

Function Related Protein
CD4 receptor bindingSPG21;PLSCR1;PLSCR4;LCK;FYN
protein bindingPPIL2;MGAT5B;GBP5;ITCH;ARIH2;MTAP1A;PSMC6;FBXW8;NBR1

SPG21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPG21 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPG21.

PRPS1; TRAF2; AGTRAP; DTX2; CTPS2

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SPG21 Products

Required fields are marked with *

My Review for All SPG21 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends