SPN
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Official Full Name
Sialophorin
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Overview
Sialophorin (leukosialin) is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which appears to be important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. -
Synonyms
Leukosialin; GALGP; OTTHUMP00000123397; GPL115; OTTHUMP00000196610; sialophorin (leukosialin, CD43); sialophorin (gpL115, leukosialin, CD43); CD43 antigen; Leukocyte sialoglycoprotein; Galactoglycoprotein; LSN; CD43; SPN; sialophorin;
- Recombinant Proteins
- Others
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E. coli
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human
- Human Cell
- Mammalian cells
- C
- His
- Fc
- Flag
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- N
- GST
- Involved Pathway
- Protein Function
- Interacting Protein
- SPN Related Articles
- SPN Related Research Area
SPN involved in several pathways and played different roles in them. We selected most pathways SPN participated on our site, such as Cell adhesion molecules (CAMs), Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | NRXN1A;MHC1UXA2;HLA-DOA;CD8B;ITGA6;CLDN15LA;ITGB1B.2;CLDN20;CNTNAP2A |
| Epstein-Barr virus infection | FCER2;HLA-F;TRADD;PIK3CD;PSMC6;CSNK2A2;PIK3R2;HLA-B;HLA-DQB1 |
SPN has several biochemical functions, for example, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPN itself. We selected most functions SPN had, and list some proteins which have the same functions with SPN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SYT2;PRKAR2AA;DLL4;RGS1;VCAN;CCDC106;CSF2;LDLRAD1;GNAI1 |
| transmembrane signaling receptor activity | TLR4;TRPV1;GHRHRA;TNFRSF11A;KLRC2;FZD9B;GPR126;TLR2-2;MPL |
SPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPN here. Most of them are supplied by our site. Hope this information will be useful for your research of SPN.
DICER1
- Q&As
- Reviews
Q&As (7)
Ask a questionSPN, or Sialophorin, is important in modulating the function of immune cells, particularly lymphocytes.
Targeting SPN could provide new treatment approaches for managing immune-related conditions, including autoimmune diseases.
Genetic changes in SPN can lead to variations in immune cell behavior and effectiveness.
SPN plays a role in regulating immune cell adhesion and migration, crucial for immune surveillance and response.
SPN interacts with other immune molecules, coordinating immune cell communication and function.
Altered SPN activity can impact the regulation of immune responses, potentially leading to autoimmune disorders.
It contributes to immune cell signaling, influencing cell activation and response to stimuli.
Customer Reviews (3)
Write a reviewAccurate and timely results, crucial for research progress.
Instrumental in our research achievements, highly trusted.
Efficient and dependable, aids our research significantly.
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